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CATH Superfamily 1.10.60.10

Iron dependent repressor, metal binding and dimerisation domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Iron dependent repressor, metal binding and dimerisation domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Mn-dependent transcriptional regulator MntR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
 160 P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA)
(150 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
 160 P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS)
(150 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 160 P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI) P0A9F1 (/IPI)
(150 more)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 160 P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA) P0A9F1 (/IDA)
(150 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
 160 P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS) P0A9F1 (/ISS)
(150 more)
Positive regulation of DNA-templated transcription, initiation GO:2000144
Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.
 160 P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP) P0A9F1 (/IEP)
(150 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.