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CATH Superfamily 1.10.580.10

Citrate Synthase, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Citrate Synthase, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Citrate synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Citrate synthase activity GO:0036440
Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
 24 I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS)
(14 more)
2-methylcitrate synthase activity GO:0050440
Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).
 24 I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS)
(14 more)
Citrate synthase activity GO:0036440
Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
 15 H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA)
(5 more)
2-methylcitrate synthase activity GO:0050440
Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).
 15 H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA)
(5 more)
2-methylcitrate synthase activity GO:0050440
Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).
 12 O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP)
(2 more)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
 24 I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP) I6Y9Q3 (/IMP)
(14 more)
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
 24 I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS) I6Y9Q3 (/ISS)
(14 more)
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
 14 H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA) H8F0D7 (/IDA)
(4 more)
Response to acidic pH GO:0010447
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
 12 O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP)
(2 more)
Propionate catabolic process, 2-methylcitrate cycle GO:0019629
The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
 12 O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP) O08395 (/IMP)
(2 more)
Response to host immune response GO:0052572
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
 12 O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP) O08395 (/IEP)
(2 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.