The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Citrate Synthase, domain 1
".
FunFam 11: Citrate synthase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Citrate (Si)-synthase activity GO:0004108
Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.
|
11 |
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
(1 more) |
|
Citrate synthase activity GO:0036440
Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
|
4 | P45858 (/ISS) P45858 (/ISS) P45858 (/ISS) P45858 (/ISS) |
|
2-methylcitrate synthase activity GO:0050440
Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).
|
4 | P45858 (/ISS) P45858 (/ISS) P45858 (/ISS) P45858 (/ISS) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
11 |
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
A0A2B6C8U7 (/ISS)
(1 more) |
|
Propionate metabolic process, methylcitrate cycle GO:0019679
The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
|
4 | P45858 (/ISS) P45858 (/ISS) P45858 (/ISS) P45858 (/ISS) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.