The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Retinoid X Receptor
".
FunFam 13: Peroxisome proliferator-activated receptor delta
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 73 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
10 | P23204 (/IPI) P23204 (/IPI) P35396 (/IPI) P35396 (/IPI) P37230 (/IPI) Q03181 (/IPI) Q03181 (/IPI) Q07869 (/IPI) Q07869 (/IPI) Q07869 (/IPI) |
|
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
|
9 | O35507 (/ISS) P23204 (/ISS) P23204 (/ISS) P35396 (/ISS) P35396 (/ISS) P37230 (/ISS) Q0ZAQ8 (/ISS) Q8HYL6 (/ISS) Q95N78 (/ISS) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
7 | Q07869 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
7 | P23204 (/IDA) P23204 (/IDA) Q03181 (/IDA) Q03181 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
7 | O35507 (/ISS) P35396 (/ISS) P35396 (/ISS) P37230 (/ISS) Q0ZAQ8 (/ISS) Q8HYL6 (/ISS) Q95N78 (/ISS) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
7 | Q07869 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
6 | Q03181 (/ISS) Q03181 (/ISS) Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
6 | F1QJT0 (/IDA) F8W3D2 (/IDA) P23204 (/IDA) P23204 (/IDA) P37230 (/IDA) Q90Z67 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | Q03181 (/ISA) Q03181 (/ISA) Q07869 (/ISA) Q07869 (/ISA) Q07869 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | Q03181 (/ISM) Q03181 (/ISM) Q07869 (/ISM) Q07869 (/ISM) Q07869 (/ISM) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | Q03181 (/NAS) Q03181 (/NAS) Q07869 (/NAS) Q07869 (/NAS) Q07869 (/NAS) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | P35396 (/IDA) P35396 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
5 | Q03181 (/IDA) Q03181 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
|
5 | P23204 (/TAS) P23204 (/TAS) P37230 (/TAS) Q03181 (/TAS) Q03181 (/TAS) |
|
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
5 | Q03181 (/IDA) Q03181 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
5 | Q03181 (/IPI) Q03181 (/IPI) Q07869 (/IPI) Q07869 (/IPI) Q07869 (/IPI) |
|
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
|
5 | Q03181 (/IDA) Q03181 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
4 | P23204 (/IDA) P23204 (/IDA) P35396 (/IDA) P35396 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Lipid binding GO:0008289
Interacting selectively and non-covalently with a lipid.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
4 | Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
4 | P23204 (/TAS) P23204 (/TAS) P35396 (/TAS) P35396 (/TAS) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
RNA polymerase II repressing transcription factor binding GO:0001103
Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription.
|
3 | Q07869 (/IPI) Q07869 (/IPI) Q07869 (/IPI) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
3 | Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
3 | P35396 (/ISS) P35396 (/ISS) Q0ZAQ8 (/ISS) |
|
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
3 | P35396 (/TAS) P35396 (/TAS) Q99ND3 (/TAS) |
|
Ubiquitin conjugating enzyme binding GO:0031624
Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins.
|
3 | Q07869 (/IPI) Q07869 (/IPI) Q07869 (/IPI) |
|
Linoleic acid binding GO:0070539
Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.
|
3 | P35396 (/ISS) P35396 (/ISS) Q0ZAQ8 (/ISS) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
RNA polymerase II repressing transcription factor binding GO:0001103
Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Transcription coactivator binding GO:0001223
Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q03181 (/NAS) Q03181 (/NAS) |
|
Steroid hormone receptor activity GO:0003707
Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
|
2 | P35396 (/TAS) P35396 (/TAS) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
2 | P23204 (/IDA) P23204 (/IDA) |
|
Prostacyclin receptor activity GO:0016501
Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.
|
2 | P35396 (/TAS) P35396 (/TAS) |
|
Phosphatase binding GO:0019902
Interacting selectively and non-covalently with any phosphatase.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Ubiquitin conjugating enzyme binding GO:0031624
Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
2 | P23204 (/IDA) P23204 (/IDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Retinoid X receptor binding GO:0046965
Interacting selectively and non-covalently with a retinoid X receptor.
|
2 | P35396 (/TAS) P35396 (/TAS) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | P35396 (/IPI) P35396 (/IPI) |
|
NF-kappaB binding GO:0051059
Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
NFAT protein binding GO:0051525
Interacting selectively and non-covalently with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Linoleic acid binding GO:0070539
Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.
|
2 | Q03181 (/IDA) Q03181 (/IDA) |
|
Linoleic acid binding GO:0070539
Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
MDM2/MDM4 family protein binding GO:0097371
Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Transcription coactivator binding GO:0001223
Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | P37230 (/IPI) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | Q99ND3 (/TAS) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q99ND3 (/IDA) |
|
Nuclear receptor activity GO:0004879
Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
|
1 | P37230 (/IMP) |
|
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
1 | Q99ND3 (/IDA) |
|
Phosphatase binding GO:0019902
Interacting selectively and non-covalently with any phosphatase.
|
1 | P37230 (/IPI) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | P37230 (/IDA) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | P37230 (/IMP) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | P37230 (/IPI) |
|
NF-kappaB binding GO:0051059
Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.
|
1 | Q99ND3 (/IPI) |
|
NFAT protein binding GO:0051525
Interacting selectively and non-covalently with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
|
1 | P37230 (/IPI) |
|
MDM2/MDM4 family protein binding GO:0097371
Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53.
|
1 | P37230 (/IPI) |
There are 179 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
10 | O35507 (/ISS) P35396 (/ISS) P35396 (/ISS) P37230 (/ISS) Q0ZAQ8 (/ISS) Q5EA13 (/ISS) Q5EA13 (/ISS) Q8HYL6 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
7 | P23204 (/TAS) P23204 (/TAS) Q03181 (/TAS) Q03181 (/TAS) Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Negative regulation of appetite GO:0032099
Any process that reduces appetite.
|
7 | O35507 (/ISS) P37230 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q8HYL6 (/ISS) Q95N78 (/ISS) |
|
Circadian regulation of gene expression GO:0032922
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
|
7 | O35507 (/ISS) P37230 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q8HYL6 (/ISS) Q95N78 (/ISS) |
|
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
|
7 | O35507 (/ISS) P37230 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q07869 (/ISS) Q8HYL6 (/ISS) Q95N78 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
6 | P23204 (/IDA) P23204 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q9I8W4 (/IDA) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
5 | P35396 (/IDA) P35396 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Transcription initiation from RNA polymerase II promoter GO:0006367
Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
|
5 | Q03181 (/TAS) Q03181 (/TAS) Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
5 | P23204 (/TAS) P23204 (/TAS) Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
|
5 | A6XMH7 (/IDA) F1QJT0 (/IDA) F8W3D2 (/IDA) K7DY57 (/IDA) Q90Z67 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | Q03181 (/IDA) Q03181 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Negative regulation of pri-miRNA transcription by RNA polymerase II GO:1902894
Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
|
5 | P35396 (/IDA) P35396 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
4 | Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
|
4 | P35396 (/TAS) P35396 (/TAS) Q03181 (/TAS) Q03181 (/TAS) |
|
Epidermis development GO:0008544
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
|
4 | Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Regulation of fatty acid metabolic process GO:0019217
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
|
4 | Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
4 | P23204 (/IMP) P23204 (/IMP) P35396 (/IMP) P35396 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | P23204 (/IMP) P23204 (/IMP) Q9MZG4 (/IMP) Q9N135 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
4 | Q5EA13 (/ISS) Q5EA13 (/ISS) Q95N78 (/ISS) Q9N129 (/ISS) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
4 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q99ND3 (/IDA) |
|
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
3 | P23204 (/IMP) P23204 (/IMP) P37230 (/IMP) |
|
Fatty acid beta-oxidation GO:0006635
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
|
3 | Q03181 (/ISS) Q03181 (/ISS) Q62879 (/ISS) |
|
Negative regulation of macrophage derived foam cell differentiation GO:0010745
Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
|
3 | Q07869 (/IC) Q07869 (/IC) Q07869 (/IC) |
|
Negative regulation of macrophage derived foam cell differentiation GO:0010745
Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Negative regulation of receptor biosynthetic process GO:0010871
Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Negative regulation of sequestering of triglyceride GO:0010891
Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
3 | F1QJT0 (/IGI) F8W3D2 (/IGI) Q90Z67 (/IGI) |
|
Fatty acid transport GO:0015908
The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
3 | Q03181 (/ISS) Q03181 (/ISS) Q62879 (/ISS) |
|
Fatty acid transport GO:0015908
The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
3 | Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
3 | Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Positive regulation of fatty acid beta-oxidation GO:0032000
Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.
|
3 | Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Negative regulation of glycolytic process GO:0045820
Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.
|
3 | Q07869 (/IC) Q07869 (/IC) Q07869 (/IC) |
|
Positive regulation of fatty acid oxidation GO:0046321
Any process that activates or increases the frequency, rate or extent of fatty acid oxidation.
|
3 | Q07869 (/ISS) Q07869 (/ISS) Q07869 (/ISS) |
|
Regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter GO:0072363
Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter GO:0072366
Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter GO:0072369
Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Negative regulation of leukocyte cell-cell adhesion GO:1903038
Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.
|
3 | Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Placenta development GO:0001890
The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
|
2 | Q03181 (/NAS) Q03181 (/NAS) |
|
Glucose metabolic process GO:0006006
The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
|
2 | P23204 (/TAS) P23204 (/TAS) |
|
Proteoglycan metabolic process GO:0006029
The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
|
2 | Q03181 (/TAS) Q03181 (/TAS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P23204 (/TAS) P23204 (/TAS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | Q03181 (/TAS) Q03181 (/TAS) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
Fatty acid metabolic process GO:0006631
The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Fatty acid beta-oxidation GO:0006635
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
|
2 | P35396 (/IEP) P35396 (/IEP) |
|
Fatty acid beta-oxidation GO:0006635
A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
|
2 | Q03181 (/TAS) Q03181 (/TAS) |
|
Vitamin A metabolic process GO:0006776
The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
2 | Q03181 (/IMP) Q03181 (/IMP) |
|
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
2 | P37230 (/IEP) Q99ND3 (/IEP) |
|
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
|
2 | P35396 (/IDA) P35396 (/IDA) |
|
Cholesterol metabolic process GO:0008203
The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
|
2 | Q03181 (/TAS) Q03181 (/TAS) |
|
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
2 | Q03181 (/TAS) Q03181 (/TAS) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Axon ensheathment GO:0008366
Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Axon ensheathment GO:0008366
Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
Epidermis development GO:0008544
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
Epidermis development GO:0008544
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
|
2 | P35396 (/TAS) P35396 (/TAS) |
|
Phospholipid biosynthetic process GO:0008654
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Fatty acid catabolic process GO:0009062
The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
|
2 | Q03181 (/TAS) Q03181 (/TAS) |
|
MRNA transcription GO:0009299
The cellular synthesis of messenger RNA (mRNA) from a DNA template.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Cellular process GO:0009987
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
|
2 | P35396 (/TAS) P35396 (/TAS) |
|
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Negative regulation of macrophage derived foam cell differentiation GO:0010745
Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of receptor biosynthetic process GO:0010871
Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of cholesterol storage GO:0010887
Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of sequestering of triglyceride GO:0010891
Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
|
2 | P35396 (/IDA) P35396 (/IDA) |
|
Regulation of skeletal muscle satellite cell proliferation GO:0014842
Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Fatty acid transport GO:0015908
The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
|
2 | P35396 (/IEP) P35396 (/IEP) |
|
Fatty acid oxidation GO:0019395
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
2 | P35396 (/IDA) P35396 (/IDA) |
|
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Cell-substrate adhesion GO:0031589
The attachment of a cell to the underlying substrate via adhesion molecules.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of appetite GO:0032099
Any process that reduces appetite.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Circadian regulation of gene expression GO:0032922
Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
|
2 | P23204 (/IDA) P23204 (/IDA) |
|
Negative regulation of collagen biosynthetic process GO:0032966
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Behavioral response to nicotine GO:0035095
Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
2 | P35396 (/IGI) P35396 (/IGI) |
|
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Lipoprotein metabolic process GO:0042157
The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
|
2 | P23204 (/IDA) P23204 (/IDA) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Positive regulation of skeletal muscle tissue regeneration GO:0043415
Any process that activates or increase the rate of skeletal muscle regeneration.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Keratinocyte proliferation GO:0043616
The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Regulation of fat cell differentiation GO:0045598
Any process that modulates the frequency, rate or extent of adipocyte differentiation.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Positive regulation of fat cell differentiation GO:0045600
Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
|
2 | Q03181 (/NAS) Q03181 (/NAS) |
|
Negative regulation of myoblast differentiation GO:0045662
Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Positive regulation of epidermis development GO:0045684
Any process that activates or increases the frequency, rate or extent of epidermis development.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Positive regulation of gluconeogenesis GO:0045722
Any process that activates or increases the frequency, rate or extent of gluconeogenesis.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
Negative regulation of blood pressure GO:0045776
Any process in which the force of blood traveling through the circulatory system is decreased.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P23204 (/IGI) P23204 (/IGI) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Positive regulation of fatty acid oxidation GO:0046321
Any process that activates or increases the frequency, rate or extent of fatty acid oxidation.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
Decidualization GO:0046697
The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
|
2 | Q03181 (/TAS) Q03181 (/TAS) |
|
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Negative regulation of epithelial cell proliferation GO:0050680
Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
|
2 | P35396 (/IGI) P35396 (/IGI) |
|
Regulation of insulin secretion GO:0050796
Any process that modulates the frequency, rate or extent of the regulated release of insulin.
|
2 | P35396 (/NAS) P35396 (/NAS) |
|
Keratinocyte migration GO:0051546
The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Adipose tissue development GO:0060612
The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Negative regulation of cell growth involved in cardiac muscle cell development GO:0061052
Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Enamel mineralization GO:0070166
The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.
|
2 | P23204 (/IMP) P23204 (/IMP) |
|
Cellular response to cold GO:0070417
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
2 | A6XMH7 (/IDA) K7DY57 (/IDA) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
2 | P35396 (/IGI) P35396 (/IGI) |
|
Regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter GO:0072363
Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter GO:0072366
Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter GO:0072369
Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Apoptotic signaling pathway GO:0097190
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
|
2 | Q03181 (/IMP) Q03181 (/IMP) |
|
Apoptotic signaling pathway GO:0097190
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
|
2 | P35396 (/ISO) P35396 (/ISO) |
|
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of pri-miRNA transcription by RNA polymerase II GO:1902894
Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Negative regulation of pri-miRNA transcription by RNA polymerase II GO:1902894
Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
Negative regulation of leukocyte cell-cell adhesion GO:1903038
Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.
|
2 | P23204 (/ISO) P23204 (/ISO) |
|
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
|
2 | Q03181 (/NAS) Q03181 (/NAS) |
|
Positive regulation of myoblast proliferation GO:2000288
Any process that activates or increases the frequency, rate or extent of myoblast proliferation.
|
2 | P35396 (/IMP) P35396 (/IMP) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
1 | P37230 (/IDA) |
|
Proteoglycan metabolic process GO:0006029
The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
|
1 | Q99ND3 (/IDA) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P37230 (/IDA) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
1 | Q99ND3 (/IDA) |
|
Lipid metabolic process GO:0006629
The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
|
1 | Q62879 (/NAS) |
|
Vitamin A metabolic process GO:0006776
The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.
|
1 | Q99ND3 (/IMP) |
|
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
|
1 | Q99ND3 (/IEP) |
|
Phospholipid biosynthetic process GO:0008654
The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
|
1 | Q99ND3 (/IDA) |
|
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
|
1 | Q62879 (/NAS) |
|
MRNA transcription GO:0009299
The cellular synthesis of messenger RNA (mRNA) from a DNA template.
|
1 | Q99ND3 (/IDA) |
|
Response to glucose GO:0009749
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
1 | Q99ND3 (/IEP) |
|
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
|
1 | Q99ND3 (/IEP) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q9N135 (/IMP) |
|
Positive regulation of cholesterol efflux GO:0010875
Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
|
1 | Q9N135 (/IMP) |
|
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
|
1 | Q99ND3 (/IEP) |
|
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
|
1 | Q99ND3 (/IDA) |
|
Regulation of fatty acid metabolic process GO:0019217
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
|
1 | P37230 (/TAS) |
|
Fatty acid oxidation GO:0019395
The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
|
1 | Q99ND3 (/IDA) |
|
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
|
1 | Q99ND3 (/IDA) |
|
Regulation of prostaglandin biosynthetic process GO:0031392
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
|
1 | Q9N135 (/IMP) |
|
Positive regulation of prostaglandin biosynthetic process GO:0031394
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
|
1 | Q9MZG4 (/IMP) |
|
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
1 | Q99ND3 (/IDA) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
1 | P37230 (/IMP) |
|
Response to insulin GO:0032868
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
1 | P37230 (/IMP) |
|
Negative regulation of collagen biosynthetic process GO:0032966
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
1 | Q99ND3 (/IMP) |
|
Response to vitamin A GO:0033189
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
|
1 | Q99ND3 (/IEP) |
|
Behavioral response to nicotine GO:0035095
Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
|
1 | P37230 (/IDA) |
|
Lipoprotein metabolic process GO:0042157
The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.
|
1 | P37230 (/IMP) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q99ND3 (/IDA) |
|
Negative regulation of I-kappaB kinase/NF-kappaB signaling GO:0043124
Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
|
1 | Q62879 (/NAS) |
|
Positive regulation of epidermis development GO:0045684
Any process that activates or increases the frequency, rate or extent of epidermis development.
|
1 | Q99ND3 (/IDA) |
|
Negative regulation of blood pressure GO:0045776
Any process in which the force of blood traveling through the circulatory system is decreased.
|
1 | P37230 (/IMP) |
|
Decidualization GO:0046697
The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
|
1 | Q99ND3 (/IEP) |
|
Response to pain GO:0048265
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
|
1 | Q62879 (/NAS) |
|
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
|
1 | Q99ND3 (/IDA) |
|
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
|
1 | Q9N135 (/IMP) |
|
Negative regulation of cell growth involved in cardiac muscle cell development GO:0061052
Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
|
1 | P37230 (/IMP) |
|
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | Q99ND3 (/IDA) |
|
Positive regulation of blood vessel diameter GO:0097755
Any process that increases the diameter of blood vessels.
|
1 | Q99ND3 (/IDA) |
|
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
|
1 | P37230 (/IDA) |
|
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
|
1 | P37230 (/IMP) |
|
Regulation of protein localization to plasma membrane GO:1903076
Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.
|
1 | Q9N135 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | F1D8S4 (/IDA) F1D8S4 (/IDA) F1D8S4 (/IDA) P35396 (/IDA) P35396 (/IDA) P37230 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q99ND3 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
7 | P23204 (/TAS) P23204 (/TAS) Q03181 (/TAS) Q03181 (/TAS) Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | F1D8S4 (/IDA) F1D8S4 (/IDA) F1D8S4 (/IDA) Q07869 (/IDA) Q07869 (/IDA) Q07869 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | P23204 (/TAS) P23204 (/TAS) Q07869 (/TAS) Q07869 (/TAS) Q07869 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P23204 (/ISO) P23204 (/ISO) P35396 (/ISO) P35396 (/ISO) |
|
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
3 | F1QJT0 (/IDA) F8W3D2 (/IDA) Q90Z67 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | P35396 (/IDA) P35396 (/IDA) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | Q03181 (/ISS) Q03181 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q03181 (/NAS) Q03181 (/NAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | P23204 (/ISO) P23204 (/ISO) |
