The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
GroEL-like equatorial domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: 60 kDa chaperonin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
24 A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI) A0A0H3LCC3 (/IPI)
(14 more)
ATPase activity, coupled GO:0042623
Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
16 Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS)
(6 more)
Host cell surface binding GO:0046812
Interacting selectively and non-covalently with the surface of a host cell.
12 A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA)
(2 more)
Unfolded protein binding GO:0051082
Interacting selectively and non-covalently with an unfolded protein.
1 Q37683 (/ISA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Adhesion of symbiont to host GO:0044406
The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.
24 A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA)
(14 more)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
16 Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS)
(6 more)
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
16 Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS)
(6 more)
Response to unfolded protein GO:0006986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
16 Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS) Q8IJN9 (/ISS)
(6 more)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
12 P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP)
(2 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
12 P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP) P9WPE7 (/IEP)
(2 more)
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
12 P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA)
(2 more)
Positive regulation of transcription regulatory region DNA binding GO:2000679
Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
12 P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA)
(2 more)
Protein folding GO:0006457
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
1 Q37683 (/ISA)
Protein import into mitochondrial matrix GO:0030150
The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.
1 Q37683 (/ISA)

There are 19 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
17 Q37683 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA) Q8IJN9 (/IDA)
(7 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA)
(2 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA)
(2 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA) P9WPE7 (/HDA)
(2 more)
Capsule GO:0042603
A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication.
12 P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA) P9WPE7 (/IDA)
(2 more)
Host cell surface GO:0044228
The external part of the host cell wall and/or host plasma membrane.
12 A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA) A0A0H3LCC3 (/IDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 Q37683 (/IDA) Q381T1 (/IDA) Q381T1 (/IDA) Q586A7 (/IDA) Q586A7 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q4Q1M0 (/ISO) Q4Q1M1 (/ISO) Q4Q594 (/ISO) Q4Q711 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q37683 (/RCA) Q381T1 (/RCA) Q381T1 (/RCA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q381T1 (/ISA) Q381T1 (/ISA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q4Q1M0 (/ISO) Q4Q1M1 (/ISO)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
2 Q4Q1M0 (/ISO) Q4Q1M1 (/ISO)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
2 Q586A7 (/IDA) Q586A7 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
2 Q586A7 (/IDA) Q586A7 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q37683 (/ISM)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q37683 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q4Q711 (/ISO)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q4Q711 (/ISO)
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