The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rho GTPase activation protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 32: Uncharacterized protein, isoform E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
8 B7Z058 (/IMP) M9MRW2 (/IMP) M9PFL1 (/IMP) M9PFR0 (/IMP) M9PFR0 (/IMP) Q8IQM3 (/IMP) Q9VUR5 (/IMP) Q9VUR6 (/IMP)
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
8 B7Z058 (/ISS) M9MRW2 (/ISS) M9PFL1 (/ISS) M9PFR0 (/ISS) M9PFR0 (/ISS) Q8IQM3 (/ISS) Q9VUR5 (/ISS) Q9VUR6 (/ISS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Apical constriction involved in gastrulation GO:0003384
The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.
8 B7Z058 (/IMP) M9MRW2 (/IMP) M9PFL1 (/IMP) M9PFR0 (/IMP) M9PFR0 (/IMP) Q8IQM3 (/IMP) Q9VUR5 (/IMP) Q9VUR6 (/IMP)
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
8 B7Z058 (/ISS) M9MRW2 (/ISS) M9PFL1 (/ISS) M9PFR0 (/ISS) M9PFR0 (/ISS) Q8IQM3 (/ISS) Q9VUR5 (/ISS) Q9VUR6 (/ISS)
Imaginal disc-derived leg morphogenesis GO:0007480
The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.
8 B7Z058 (/IMP) M9MRW2 (/IMP) M9PFL1 (/IMP) M9PFR0 (/IMP) M9PFR0 (/IMP) Q8IQM3 (/IMP) Q9VUR5 (/IMP) Q9VUR6 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
8 B7Z058 (/IDA) M9MRW2 (/IDA) M9PFL1 (/IDA) M9PFR0 (/IDA) M9PFR0 (/IDA) Q8IQM3 (/IDA) Q9VUR5 (/IDA) Q9VUR6 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...