The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Acyl-CoA dehydrogenase/oxidase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Isovaleryl-CoA dehydrogenase, mitochondrial

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Isovaleryl-CoA dehydrogenase. [EC: 1.3.8.4]
Isovaleryl-CoA + electron-transfer flavoprotein = 3-methylcrotonyl-CoA + reduced electron-transfer flavoprotein.
  • Pentanoate can act as donor.
  • Formerly EC 1.3.99.10.
14 A0A0A0MT83 A0A0A0MT83 P12007 P26440 P26440 Q0WPE4 Q0WPE4 Q3SZI8 Q5RBD5 Q75IM9
(4 more...)
2-methylacyl-CoA dehydrogenase. [EC: 1.3.99.12]
2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor.
  • Also oxidizes 2-methylpropanoyl-CoA.
  • Not identical with EC 1.3.8.1, EC 1.3.8.7, EC 1.3.8.8 or EC 1.3.8.9.
1 Q9FS88
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