The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 954: Tyrosine-protein kinase-like otk

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
9 B3MH43 (/ISS) B3NS99 (/ISS) B4GBH0 (/ISS) B4HNW4 (/ISS) B4KPU0 (/ISS) B4MR28 (/ISS) B4P5Q9 (/ISS) B4QC63 (/ISS) Q290N5 (/ISS)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
9 B3MH43 (/ISS) B3NS99 (/ISS) B4GBH0 (/ISS) B4HNW4 (/ISS) B4KPU0 (/ISS) B4MR28 (/ISS) B4P5Q9 (/ISS) B4QC63 (/ISS) Q290N5 (/ISS)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
9 B3MH43 (/ISS) B3NS99 (/ISS) B4GBH0 (/ISS) B4HNW4 (/ISS) B4KPU0 (/ISS) B4MR28 (/ISS) B4P5Q9 (/ISS) B4QC63 (/ISS) Q290N5 (/ISS)
Transmembrane receptor protein tyrosine kinase activity GO:0004714
Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
1 Q6AWJ9 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q6AWJ9 (/IPI)
Wnt-protein binding GO:0017147
Interacting selectively and non-covalently with Wnt-protein, a secreted growth factor involved in signaling.
1 Q6AWJ9 (/IPI)
Semaphorin receptor binding GO:0030215
Interacting selectively and non-covalently with semaphorin receptors.
1 Q6AWJ9 (/TAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q6AWJ9 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q6AWJ9 (/IPI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
1 Q6AWJ9 (/IDA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
9 B3MH43 (/ISS) B3NS99 (/ISS) B4GBH0 (/ISS) B4HNW4 (/ISS) B4KPU0 (/ISS) B4MR28 (/ISS) B4P5Q9 (/ISS) B4QC63 (/ISS) Q290N5 (/ISS)
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
9 B3MH43 (/ISS) B3NS99 (/ISS) B4GBH0 (/ISS) B4HNW4 (/ISS) B4KPU0 (/ISS) B4MR28 (/ISS) B4P5Q9 (/ISS) B4QC63 (/ISS) Q290N5 (/ISS)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 Q6AWJ9 (/IDA)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 Q6AWJ9 (/IGI)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 Q6AWJ9 (/IMP)
Retinal ganglion cell axon guidance GO:0031290
The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
1 Q6AWJ9 (/IMP)
Internal genitalia morphogenesis GO:0035260
The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.
1 Q6AWJ9 (/IGI)
Imaginal disc-derived male genitalia morphogenesis GO:0048803
The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc.
1 Q6AWJ9 (/IGI)
Imaginal disc-derived female genitalia morphogenesis GO:0048804
The process in which the anatomical structures of female genitalia are generated and organized from the genital disc.
1 Q6AWJ9 (/IGI)
Photoreceptor cell axon guidance GO:0072499
The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.
1 Q6AWJ9 (/IMP)
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
1 Q6AWJ9 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 B3MH43 (/ISS) B3NS99 (/ISS) B4GBH0 (/ISS) B4HNW4 (/ISS) B4KPU0 (/ISS) B4MR28 (/ISS) B4P5Q9 (/ISS) B4QC63 (/ISS) Q290N5 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q6AWJ9 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q6AWJ9 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6AWJ9 (/ISM)
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