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CATH Superfamily 1.10.510.10

Transferase(Phosphotransferase) domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 82: Shaggy-related protein kinase kappa

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Dual-specificity kinase. [EC: 2.7.12.1]
ATP + a protein = ADP + a phosphoprotein.
  • This family of enzymes can phosphorylate both Ser/Thr and Tyr residues.
  • Formerly EC 2.7.1.37.
 81 A0A0L8VIY8 A0A0L8VIY8 A0A0L8VIY8 A0A0L8VIY8 A0A0L8VIY8 A0A0L8VIY8 A0A0L8VIY8 A0A0L8VIY8 A0A0L8VIY8 A6ZSH3
(71 more...)
Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
ATP + a protein = ADP + a phosphoprotein.
  • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
  • Formerly EC 2.7.1.37 and EC 2.7.1.70.
 69 A0A087GF91 A0A087GF91 A0A0D3GHM3 A0A0D3GHM3 A0A0D3GHM3 A0A0D3GHM3 A0A0D3GHM3 A0A0E0AAP9 A0A0E0AAP9 A0A0E0AAP9
(59 more...)
[Tau protein] kinase. [EC: 2.7.11.26]
ATP + [tau protein] = ADP + [tau protein] phosphate.
  • Activated by tubulin.
  • Involved in the formation of paired helical filaments, which are the main fibrous component of all fibrillary lesions in brain and are associated with Alzheimer's disease.
  • Formerly EC 2.7.1.135.
 16 A0A1G4IBC5 A0A1G4IBC5 A0A1G4IBC5 A0A1G4IBC5 A0A3L6L0Y8 A0A3L6L0Y8 A0A3L6L0Y8 A0A3L6L0Y8 D0A032 D0A032
(6 more...)