The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Transferase(Phosphotransferase) domain 1
".
FunFam 706: Cyclin-dependent kinase 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
1 | P34556 (/IDA) |
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
|
1 | P34556 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O61847 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | P34556 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | A8XA58 (/ISS) |
There are 27 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | P34556 (/IMP) |
Oocyte maturation GO:0001556
A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
|
1 | P34556 (/IMP) |
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
|
1 | O61847 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | P34556 (/IDA) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
1 | O61847 (/IMP) |
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
1 | O61847 (/IMP) |
Anterior/posterior axis specification, embryo GO:0008595
The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.
|
1 | P34556 (/IGI) |
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
1 | O61847 (/IMP) |
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
|
1 | O61847 (/IGI) |
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
|
1 | O61847 (/IMP) |
Pseudocleavage GO:0030588
Partial constriction of the cytoplasm of an embryo to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.
|
1 | O61847 (/IMP) |
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | P34556 (/IMP) |
Positive regulation of meiotic nuclear division GO:0045836
Any process that activates or increases the frequency, rate or extent of meiosis.
|
1 | P34556 (/IMP) |
Hermaphrodite genitalia morphogenesis GO:0048815
The process in which the anatomical structures of hermaphrodite genitalia are generated and organized.
|
1 | O61847 (/IMP) |
Nuclear envelope disassembly GO:0051081
The controlled breakdown of the nuclear envelope in the context of a normal process.
|
1 | O61847 (/IMP) |
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
|
1 | P34556 (/IMP) |
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
|
1 | A8XA58 (/ISS) |
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
|
1 | P34556 (/IMP) |
Regulation of meiotic cell cycle GO:0051445
Any process that modulates the rate or extent of progression through the meiotic cell cycle.
|
1 | O61847 (/IMP) |
Positive regulation of meiotic cell cycle GO:0051446
Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
|
1 | P34556 (/IMP) |
Positive regulation of meiotic cell cycle GO:0051446
Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
|
1 | A8XA58 (/ISS) |
Germline cell cycle switching, mitotic to meiotic cell cycle GO:0051729
The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.
|
1 | O61847 (/IGI) |
Germline cell cycle switching, mitotic to meiotic cell cycle GO:0051729
The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.
|
1 | O61847 (/IMP) |
Negative regulation of cell division GO:0051782
Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
|
1 | O61847 (/IMP) |
Positive regulation of protein serine/threonine kinase activity GO:0071902
Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
|
1 | P34556 (/IMP) |
Regulation of protein localization to cell cortex GO:1904776
Any process that modulates the frequency, rate or extent of protein localization to cell cortex.
|
1 | O61847 (/IMP) |
Positive regulation of protein localization to centrosome GO:1904781
Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.
|
1 | O61847 (/IGI) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
|
1 | O61847 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P34556 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P34556 (/IDA) |