The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 524: Cell division protein kinase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
6 P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
6 P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA)
Cyclin-dependent protein serine/threonine kinase activity GO:0004693
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
5 P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
5 P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
6 P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI)
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Regulation of transcription involved in G1/S transition of mitotic cell cycle GO:0000083
Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
6 P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA) P17157 (/HDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
6 P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Positive regulation of macroautophagy GO:0016239
Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Negative regulation of macroautophagy GO:0016242
Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
6 P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI) P17157 (/HGI)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Regulation of establishment or maintenance of cell polarity GO:0032878
Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
6 P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA)
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Negative regulation of glycogen biosynthetic process GO:0045719
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
6 P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP) P17157 (/IMP)
Negative regulation of phosphate metabolic process GO:0045936
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Negative regulation of calcium-mediated signaling GO:0050849
Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
6 P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI) P17157 (/IGI)
Positive regulation of phospholipid biosynthetic process GO:0071073
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
6 P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA)
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
5 P38973 (/TAS) P38973 (/TAS) P38973 (/TAS) P38973 (/TAS) P38973 (/TAS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
5 P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM) P38973 (/ISM)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
6 P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI) P17157 (/IPI)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA)
Pho85-Pho80 CDK-cyclin complex GO:1990860
A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.
6 P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA) P17157 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
5 P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA) P38973 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q4QC88 (/ISO)
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