The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 470: Ephrin type-B receptor 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ephrin receptor activity GO:0005003
Combining with an ephrin to initiate a change in cell activity.
1 O15197 (/TAS)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
1 O15197 (/TAS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Type IV hypersensitivity GO:0001806
An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.
1 O08644 (/IMP)
T cell mediated immunity GO:0002456
Any process involved in the carrying out of an immune response by a T cell.
1 O08644 (/IMP)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 O08644 (/IMP)
Ephrin receptor signaling pathway GO:0048013
The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
1 O15197 (/TAS)
Cytokine secretion GO:0050663
The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
1 O08644 (/IMP)
Activated T cell proliferation GO:0050798
The expansion of a T cell population following activation by an antigenic stimulus.
1 O08644 (/IMP)
Positive regulation of T cell costimulation GO:2000525
Any process that activates or increases the frequency, rate or extent of T cell costimulation.
1 O08644 (/IGI)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 O15197 (/TAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O15197 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O15197 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 O08644 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...