The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 420: Guanylate cyclase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Guanylate cyclase activity GO:0004383
Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
7 C7LAF5 (/ISS) M9NFA6 (/ISS) Q07553 (/ISS) Q8IQK2 (/ISS) Q961R7 (/ISS) Q9VF17 (/ISS) Q9VU79 (/ISS)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
7 C7LAF5 (/ISS) M9NFA6 (/ISS) Q07553 (/ISS) Q8IQK2 (/ISS) Q961R7 (/ISS) Q9VF17 (/ISS) Q9VU79 (/ISS)
Guanylate cyclase activity GO:0004383
Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
1 Q86GV3 (/IDA)
Guanylate cyclase activity GO:0004383
Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
1 Q07553 (/NAS)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
1 Q07553 (/NAS)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
CGMP-mediated signaling GO:0019934
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
7 C7LAF5 (/ISS) M9NFA6 (/ISS) Q07553 (/ISS) Q8IQK2 (/ISS) Q961R7 (/ISS) Q9VF17 (/ISS) Q9VU79 (/ISS)
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)
Negative regulation of cell size GO:0045792
Any process that reduces cell size.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
4 C7LAF5 (/IMP) M9NFA6 (/IMP) Q8IQK2 (/IMP) Q9VU79 (/IMP)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 Q86GV3 (/IMP)
Sensory perception of chemical stimulus GO:0007606
The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 Q86GV3 (/IGI)
Sensory perception of chemical stimulus GO:0007606
The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
1 Q86GV3 (/IMP)
CGMP-mediated signaling GO:0019934
Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
1 Q07553 (/NAS)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q86GV3 (/IMP)
Sensory processing GO:0050893
Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.
1 Q86GV3 (/IGI)
Sensory processing GO:0050893
Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.
1 Q86GV3 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
7 C7LAF5 (/ISS) M9NFA6 (/ISS) Q07553 (/ISS) Q8IQK2 (/ISS) Q961R7 (/ISS) Q9VF17 (/ISS) Q9VU79 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q07553 (/NAS)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q86GV3 (/IDA)
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
1 Q86GV3 (/IDA)
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