The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 156: Serine/threonine-protein kinase SIK3 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
7 A0A0B4LFW1 (/ISS) A1ZBC4 (/ISS) A8DYI4 (/ISS) A8DYI5 (/ISS) Q4QQA7 (/ISS) Q6NSM8 (/ISS) Q6P4S6 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
2 Q6NSM8 (/ISS) Q6P4S6 (/ISS)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
2 A1ZBC4 (/IDA) Q9Y2K2 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q6P4S6 (/IPI) Q9Y2K2 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 Q6NSM8 (/ISS) Q6P4S6 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q9Y2K2 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q6P4S6 (/ISO)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 A1ZBC4 (/IMP)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q6P4S6 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9Y2K2 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q6P4S6 (/ISO)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
7 A0A0B4LFW1 (/ISS) A1ZBC4 (/ISS) A8DYI4 (/ISS) A8DYI5 (/ISS) Q4QQA7 (/ISS) Q6NSM8 (/ISS) Q6P4S6 (/ISS)
Endochondral ossification GO:0001958
Replacement ossification wherein bone tissue replaces cartilage.
1 Q6P4S6 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q9Y2K2 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q6P4S6 (/ISO)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
1 A1ZBC4 (/IDA)
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
1 A1ZBC4 (/IGI)
Negative regulation of triglyceride catabolic process GO:0010897
Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
1 A1ZBC4 (/IMP)
Peptidyl-threonine phosphorylation GO:0018107
The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
1 A1ZBC4 (/IMP)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
1 Q6P4S6 (/IMP)
Limb morphogenesis GO:0035108
The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
1 Q6P4S6 (/IMP)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 Q6P4S6 (/IMP)
Negative regulation of protein import into nucleus GO:0042308
Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.
1 A1ZBC4 (/IMP)
Response to starvation GO:0042594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
1 A1ZBC4 (/IMP)
Skeletal system morphogenesis GO:0048705
The process in which the anatomical structures of the skeleton are generated and organized.
1 Q6P4S6 (/IMP)
Circadian sleep/wake cycle, sleep GO:0050802
The part of the circadian sleep/wake cycle where the organism is asleep.
1 A1ZBC4 (/IMP)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
1 A1ZBC4 (/IMP)
Cartilage development involved in endochondral bone morphogenesis GO:0060351
The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.
1 Q6P4S6 (/IMP)
Positive regulation of TORC1 signaling GO:1904263
Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
1 Q9Y2K2 (/IMP)
Positive regulation of TORC1 signaling GO:1904263
Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
1 Q6P4S6 (/ISO)
Positive regulation of TORC1 signaling GO:1904263
Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
1 Q6P4S6 (/ISS)
Positive regulation of TORC2 signaling GO:1904515
Any process that activates or increases the frequency, rate or extent of TORC2 signaling.
1 Q9Y2K2 (/IMP)
Positive regulation of TORC2 signaling GO:1904515
Any process that activates or increases the frequency, rate or extent of TORC2 signaling.
1 Q6P4S6 (/ISO)
Positive regulation of TORC2 signaling GO:1904515
Any process that activates or increases the frequency, rate or extent of TORC2 signaling.
1 Q6P4S6 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 H0Y4E8 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q6P4S6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q6P4S6 (/IDA)
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