The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 155: Casein kinase I isoform epsilon

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
21 P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA)
(11 more)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
20 P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS)
(10 more)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
19 P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA)
(9 more)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
19 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(9 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 P49674 (/IPI) P49674 (/IPI) P49674 (/IPI) P49674 (/IPI) P49674 (/IPI) P49674 (/IPI) P49674 (/IPI) P49674 (/IPI) P49674 (/IPI) P49674 (/IPI)
(9 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
18 P49674 (/HDA) P49674 (/HDA) P49674 (/HDA) P49674 (/HDA) P49674 (/HDA) P49674 (/HDA) P49674 (/HDA) P49674 (/HDA) P49674 (/HDA) P49674 (/HDA)
(8 more)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q9JMK2 (/IGI)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q9JMK2 (/ISO)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q9JMK2 (/ISO)
Showing 1 to 9 of 9 entries

There are 42 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
21 P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA)
(11 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
20 P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS)
(10 more)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
20 P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS)
(10 more)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
19 P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA)
(9 more)
Positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation GO:1905426
Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.
19 P49674 (/NAS) P49674 (/NAS) P49674 (/NAS) P49674 (/NAS) P49674 (/NAS) P49674 (/NAS) P49674 (/NAS) P49674 (/NAS) P49674 (/NAS) P49674 (/NAS)
(9 more)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
18 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(8 more)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
18 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(8 more)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
18 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(8 more)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
18 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(8 more)
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
18 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(8 more)
Showing 1 to 10 of 42 entries

There are 15 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
20 P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA) P49674 (/IDA)
(10 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
19 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(9 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
19 P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS) P49674 (/TAS)
(9 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
18 P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS) P49674 (/ISS)
(8 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q99PS2 (/IDA) Q9JJ76 (/IDA) Q9JMK2 (/IDA)
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
2 Q99PS2 (/IDA) Q9JJ76 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
2 Q99PS2 (/IDA) Q9JJ76 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 Q99PS2 (/IDA) Q9JJ76 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
1 Q0VC49 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9JMK2 (/ISO)
Showing 1 to 10 of 15 entries
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