The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1069: Germinal center kinase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 H2L099 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 H2L099 (/IPI)
Mitogen-activated protein kinase binding GO:0051019
Interacting selectively and non-covalently with a mitogen-activated protein kinase.
1 H2L099 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 H2L099 (/IMP)
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
1 H2L099 (/IMP)
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
1 H2L099 (/IMP)
Regulation of oocyte development GO:0060281
Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
1 H2L099 (/IMP)
Epithelial tube morphogenesis GO:0060562
The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
1 H2L099 (/IDA)
Regulation of Golgi organization GO:1903358
Any process that modulates the frequency, rate or extent of Golgi organization.
1 H2L099 (/IMP)
Positive regulation of endocytic recycling GO:2001137
Any process that activates or increases the frequency, rate or extent of endocytic recycling.
1 H2L099 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 H2L099 (/IDA)
Cytoplasmic side of apical plasma membrane GO:0098592
The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.
1 H2L099 (/IDA)
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