The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ypt/Rab-GAP domain of gyp1p, domain 3
".
FunFam 12: Small G protein signaling modulator 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q8VCZ6 (/IPI) Q96HU1 (/IPI) Q96HU1 (/IPI) |
|
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
3 | Q2KI13 (/ISS) Q6P6R7 (/ISS) Q8VCZ6 (/ISS) |
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
2 | Q96HU1 (/IDA) Q96HU1 (/IDA) |
|
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
2 | Q96HU1 (/IDA) Q96HU1 (/IDA) |
|
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
2 | Q96HU1 (/IPI) Q96HU1 (/IPI) |
|
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q8VCZ6 (/ISO) |
|
Rab GTPase binding GO:0017137
Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
|
1 | Q8VCZ6 (/ISO) |
|
GTPase regulator activity GO:0030695
Modulates the rate of GTP hydrolysis by a GTPase.
|
1 | Q8VCZ6 (/NAS) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of Rab protein signal transduction GO:0032483
Any process that modulates the frequency, rate or extent of Rab protein signal transduction.
|
3 | Q2KI13 (/ISS) Q6P6R7 (/ISS) Q8VCZ6 (/ISS) |
|
Rap protein signal transduction GO:0032486
A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
|
3 | Q2KI13 (/ISS) Q6P6R7 (/ISS) Q8VCZ6 (/ISS) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
3 | Q9VFB6 (/ISS) Q9VFB6 (/ISS) Q9VFB6 (/ISS) |
|
Regulation of Rab protein signal transduction GO:0032483
Any process that modulates the frequency, rate or extent of Rab protein signal transduction.
|
2 | Q96HU1 (/IEP) Q96HU1 (/IEP) |
|
Rap protein signal transduction GO:0032486
A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
|
2 | Q96HU1 (/IEP) Q96HU1 (/IEP) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
2 | Q96HU1 (/IDA) Q96HU1 (/IDA) |
|
Plasma membrane to endosome transport GO:0048227
Transport of a vesicle from the plasma membrane to the endosome.
|
2 | Q96HU1 (/IMP) Q96HU1 (/IMP) |
|
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
|
1 | Q8VCZ6 (/ISO) |
|
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q8VCZ6 (/IDA) |
|
Plasma membrane to endosome transport GO:0048227
Transport of a vesicle from the plasma membrane to the endosome.
|
1 | Q8VCZ6 (/ISO) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q9VFB6 (/ISS) Q9VFB6 (/ISS) Q9VFB6 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q96HU1 (/IDA) Q96HU1 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8VCZ6 (/ISO) |
|
Gap junction GO:0005921
A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.
|
1 | Q8VCZ6 (/IDA) |
