The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Intergrase catalytic core
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Tyrosine recombinase XerD

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Site-specific recombinase activity GO:0009009
Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences.
142 P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA)
(132 more)
Tyrosine-based site-specific recombinase activity GO:0009037
Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.
142 P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP)
(132 more)
Site-specific recombinase activity GO:0009009
Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences.
10 Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasmid maintenance GO:0006276
The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.
142 P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP)
(132 more)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
142 P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP) P0A8P8 (/IMP)
(132 more)
Resolution of recombination intermediates GO:0071139
The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.
142 P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA)
(132 more)
DNA recombination GO:0006310
Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
10 Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS) Q9KPE9 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Holliday junction resolvase complex GO:0048476
An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.
142 P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA) P0A8P8 (/IDA)
(132 more)
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