The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ncd80 complex, Nuf2 subunit
".
FunFam 21: Kinetochore protein nuf2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q10173 (/IPI) |
There are 2 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Attachment of mitotic spindle microtubules to kinetochore GO:0051315
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
|
1 | Q10173 (/IMP) |
|
Attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation GO:0051455
The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs.
|
1 | Q10173 (/IC) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromosome, centromeric region GO:0000775
The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
|
1 | Q10173 (/IDA) |
|
Condensed nuclear chromosome kinetochore GO:0000778
A multisubunit complex that is located at the centromeric region of a condensed nuclear chromosome and provides an attachment point for the spindle microtubules.
|
1 | Q10173 (/IDA) |
|
Ndc80 complex GO:0031262
An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
|
1 | Q10173 (/IDA) |
|
NMS complex GO:0031617
A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes.
|
1 | Q10173 (/IDA) |
|
Meiotic spindle pole body GO:0035974
The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | Q10173 (/IDA) |