The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ncd80 complex, Ncd80 subunit
".
FunFam 4: Kinetochore protein ndc-80
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q17635 (/IPI) |
|
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | Q17635 (/IPI) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | Q17635 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitotic chromosome movement towards spindle pole GO:0007079
The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
|
1 | Q17635 (/IGI) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
1 | Q17635 (/IMP) |
|
Protein localization to kinetochore GO:0034501
Any process in which a protein is transported to, or maintained at, the kinetochore.
|
1 | Q17635 (/IMP) |
|
Gonad morphogenesis GO:0035262
The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
|
1 | Q17635 (/IMP) |
|
Attachment of mitotic spindle microtubules to kinetochore GO:0051315
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
|
1 | Q17635 (/IMP) |
|
Positive regulation of mitotic sister chromatid separation GO:1901970
Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.
|
1 | Q17635 (/IGI) |
|
Protein localization to kinetochore involved in kinetochore assembly GO:1903394
Any protein localization to kinetochore that is involved in kinetochore assembly.
|
1 | Q17635 (/IMP) |
|
Positive regulation of protein localization to kinetochore GO:1905342
Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore.
|
1 | Q17635 (/IMP) |
|
Positive regulation of kinetochore assembly GO:1905561
Any process that activates or increases the frequency, rate or extent of kinetochore assembly.
|
1 | Q17635 (/IGI) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
1 | Q17635 (/IDA) |
|
Ndc80 complex GO:0031262
An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.
|
1 | Q17635 (/IDA) |