The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (C-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Adenylosuccinate lyase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3-carboxymuconate cycloisomerase type II activity GO:0018842
Catalysis of the reaction: 3-sulfomuconate = 4-sulfolactone.
11 Q48JV9 (/ISS) Q48JV9 (/ISS) Q48JV9 (/ISS) Q48JV9 (/ISS) Q48JV9 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS)
(1 more)
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity GO:0004018
Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.
6 P12047 (/IDA) P12047 (/IDA) P12047 (/IDA) P12047 (/IDA) P12047 (/IDA) P12047 (/IDA)
Carbon-nitrogen lyase activity GO:0016840
Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
1 O42889 (/ISM)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Catechol-containing compound metabolic process GO:0009712
The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.
11 Q48JV9 (/ISS) Q48JV9 (/ISS) Q48JV9 (/ISS) Q48JV9 (/ISS) Q48JV9 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS) Q883L5 (/ISS)
(1 more)
AMP biosynthetic process GO:0006167
The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.
6 P12047 (/IDA) P12047 (/IDA) P12047 (/IDA) P12047 (/IDA) P12047 (/IDA) P12047 (/IDA)
Respiratory gaseous exchange by respiratory system GO:0007585
The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.
1 Q15247 (/TAS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O42889 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O42889 (/HDA)
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