The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (C-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Adenylosuccinate lyase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity GO:0004018
Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.
72 P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA)
(62 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
72 P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI) P0AB89 (/IPI)
(62 more)
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity GO:0004018
Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.
8 Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
72 P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP) P0AB89 (/IEP)
(62 more)
Purine ribonucleotide biosynthetic process GO:0009152
The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
8 Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS) Q9KSY0 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
72 P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA) P0AB89 (/IDA)
(62 more)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
2 Q8GUN7 (/IDA) Q8RY94 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q8RY94 (/IDA)
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