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CATH Superfamily 1.10.357.140

UbiA prenyltransferase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
UbiA prenyltransferase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
1,4-dihydroxy-2-naphthoate polyprenyltransferase. [EC: 2.5.1.74]
An all-trans-polyprenyl diphosphate + 1,4-dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO(2).
  • This enzyme catalyzes a step in the synthesis of menaquinone, in which the prenyl chain synthesized by polyprenyl diphosphate synthase is transferred to 1,4-dihydroxy-2-naphthoate (DHNA).
  • The bacterial enzyme is an inner membrane protein, with the C-terminus located in the periplasm.
  • It is highly specific for DHNA but not for a specific length of the prenyl chain.
 20 A0A1B2B0E2 A0A1B2B0E2 A0A1B2B0E2 A0A1B2B0E2 A0A410R6U3 A0A410R6U3 A0A410R6U3 A0A410R6U3 A0A410ZZV2 A0A410ZZV2
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