The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
UbiA prenyltransferase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Protoheme IX farnesyltransferase, mitochondrial

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Heme o synthase. [EC: 2.5.1.141]
(2E,6E)-farnesyl diphosphate + protoheme IX = diphosphate + ferroheme o.
  • The enzyme, found in many archaea, bacteria, and eukaryotes, produces heme o, which in many cases is further modified into heme a.
  • In organisms that produce heme a, the enzyme forms a complex with heme a synthase.
  • In some archaeal species the enzyme transfers a geranylgeranyl group instead of a farnesyl group.
16 A0A1D8NPQ5 A0A1D8NPQ5 K7AM66 K7AM66 Q12887 Q12887 Q3U3N1 Q3U3N1 Q4WP81 Q5BCK8
(6 more...)
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