The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Tetracycline Repressor, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 27: HTH-type transcriptional regulator EthR

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI) P9WMC1 (/IPI)
(2 more)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
26 A0R666 (/IMP) A0R666 (/IMP) P9WMC1 (/IMP) P9WMC1 (/IMP) P9WMC1 (/IMP) P9WMC1 (/IMP) P9WMC1 (/IMP) P9WMC1 (/IMP) P9WMC1 (/IMP) P9WMC1 (/IMP)
(16 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
12 P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA) P9WMC1 (/IDA)
(2 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
12 P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP) P9WMC1 (/IEP)
(2 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA) P9WMC1 (/HDA)
(2 more)
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