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CATH Superfamily 1.10.357.10

Tetracycline Repressor, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Tetracycline Repressor, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Nucleoid occlusion factor SlmA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
 133 P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA)
(123 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 133 P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI)
(123 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 133 P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI) P0C093 (/IPI)
(123 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
 133 P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA)
(123 more)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
 1 Q9KVD2 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Division septum site selection GO:0000918
The process of marking the site where a division septum will form.
 133 P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP) P0C093 (/IMP)
(123 more)
Negative regulation of division septum assembly GO:0010974
Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
 133 P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA)
(123 more)
Negative regulation of division septum assembly GO:0010974
Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
 133 P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI) P0C093 (/IGI)
(123 more)
Negative regulation of protein polymerization GO:0032272
Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.
 133 P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA)
(123 more)
Positive regulation of GTPase activity GO:0043547
Any process that activates or increases the activity of a GTPase.
 133 P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA)
(123 more)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
 1 Q9KVD2 (/ISS)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial nucleoid GO:0043590
The region of a bacterial cell to which the DNA is confined.
 133 P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA) P0C093 (/IDA)
(123 more)