The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Tetracycline Repressor, domain 2
".
FunFam 19: LuxR family transcriptional regulator
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 10 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
13 |
A0A0H3Q915 (/IDA)
A0A0H3Q915 (/IDA)
A0A0H3Q915 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q7MHU7 (/IDA)
(3 more) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
9 | A0A0H3Q915 (/IPI) A0A0H3Q915 (/IPI) A0A0H3Q915 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
9 | A0A0H3Q915 (/IDA) A0A0H3Q915 (/IDA) A0A0H3Q915 (/IDA) Q79YV4 (/IDA) Q79YV4 (/IDA) Q79YV4 (/IDA) Q79YV4 (/IDA) Q79YV4 (/IDA) Q79YV4 (/IDA) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
9 | A0A0H3Q915 (/IPI) A0A0H3Q915 (/IPI) A0A0H3Q915 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
7 | A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
7 | A0A0H3Q915 (/IDA) A0A0H3Q915 (/IDA) A0A0H3Q915 (/IDA) Q7MHU7 (/IDA) Q7MHU7 (/IDA) Q7MHU7 (/IDA) Q7MHU7 (/IDA) |
|
DNA-binding transcription activator activity GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by a RNA polymerase.
|
4 | Q7MHU7 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
3 | A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | A0A0H3Q915 (/IDA) A0A0H3Q915 (/IDA) A0A0H3Q915 (/IDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
9 | A0A0H3Q915 (/IEP) A0A0H3Q915 (/IEP) A0A0H3Q915 (/IEP) Q79YV4 (/IEP) Q79YV4 (/IEP) Q79YV4 (/IEP) Q79YV4 (/IEP) Q79YV4 (/IEP) Q79YV4 (/IEP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q7MHU7 (/EXP) Q7MHU7 (/EXP) Q7MHU7 (/EXP) Q7MHU7 (/EXP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | A0A0H3Q915 (/EXP) A0A0H3Q915 (/EXP) A0A0H3Q915 (/EXP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | A0A0H3Q915 (/IEP) A0A0H3Q915 (/IEP) A0A0H3Q915 (/IEP) |
|
Bioluminescence GO:0008218
The production of light by certain enzyme-catalyzed reactions in cells.
|
2 | Q5E2S4 (/IMP) Q5E2S4 (/IMP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | Q5E2S4 (/IDA) Q5E2S4 (/IDA) |
|
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
|
2 | Q8KX64 (/EXP) Q8KX64 (/EXP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8GBU2 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8GBU2 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
13 |
A0A0H3Q915 (/IDA)
A0A0H3Q915 (/IDA)
A0A0H3Q915 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q79YV4 (/IDA)
Q7MHU7 (/IDA)
(3 more) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
9 | A0A0H3Q915 (/IPI) A0A0H3Q915 (/IPI) A0A0H3Q915 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) Q79YV4 (/IPI) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
7 | A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) A0A0H3Q915 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) Q7MHU7 (/IMP) |
