The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"High mobility group box domain
".
FunFam 7: Transcription factor SOX
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 34 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
12 |
D3ZZ13 (/ISS)
E2RH58 (/ISS)
F1RUF9 (/ISS)
F1S9L1 (/ISS)
O15370 (/ISS)
O15370 (/ISS)
P35716 (/ISS)
P35716 (/ISS)
Q06945 (/ISS)
Q06945 (/ISS)
(2 more) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
12 |
D3ZZ13 (/ISS)
E2RH58 (/ISS)
F1RUF9 (/ISS)
F1S9L1 (/ISS)
O15370 (/ISS)
O15370 (/ISS)
P35716 (/ISS)
P35716 (/ISS)
Q06945 (/ISS)
Q06945 (/ISS)
(2 more) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
10 | D3ZZ13 (/ISS) E2RH58 (/ISS) F1RUF9 (/ISS) F1S9L1 (/ISS) O15370 (/ISS) O15370 (/ISS) P35716 (/ISS) P35716 (/ISS) Q0VCF8 (/ISS) Q6X895 (/ISS) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
7 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | O15370 (/ISA) O15370 (/ISA) P35716 (/ISA) P35716 (/ISA) Q06945 (/ISA) Q06945 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | O15370 (/ISM) O15370 (/ISM) P35716 (/ISM) P35716 (/ISM) Q06945 (/ISM) Q06945 (/ISM) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | O15370 (/NAS) O15370 (/NAS) P35716 (/NAS) P35716 (/NAS) Q06945 (/NAS) Q06945 (/NAS) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | P0C1G9 (/IDA) Q04890 (/IDA) Q06831 (/IDA) Q06945 (/IDA) Q06945 (/IDA) Q7M6Y2 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | P0C1G9 (/IPI) P40650 (/IPI) Q06831 (/IPI) Q06945 (/IPI) Q06945 (/IPI) Q91731 (/IPI) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
6 | P40650 (/IDA) P40656 (/IDA) P40656 (/IDA) Q8AXQ4 (/IDA) Q8AXQ4 (/IDA) Q91731 (/IDA) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
5 | P35716 (/IDA) P35716 (/IDA) Q06831 (/IDA) Q06945 (/IDA) Q06945 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
5 | P0C1G9 (/IDA) Q06831 (/IDA) Q06945 (/IDA) Q06945 (/IDA) Q7M6Y2 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
4 | P0C1G9 (/IDA) Q04890 (/IDA) Q06831 (/IDA) Q7M6Y2 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
4 | P0C1G9 (/IDA) Q04890 (/IDA) Q06831 (/IDA) Q7M6Y2 (/IDA) |
|
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
3 | P35716 (/IDA) P35716 (/IDA) Q7M6Y2 (/IDA) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | Q06831 (/ISO) Q7M6Y2 (/ISO) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | F1RUF9 (/ISS) Q0VCF8 (/ISS) |
|
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
2 | F1S9L1 (/ISS) P0C1G9 (/ISS) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q06831 (/ISO) Q7M6Y2 (/ISO) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | O15370 (/NAS) O15370 (/NAS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | P0C1G9 (/TAS) Q8T3B9 (/TAS) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q06945 (/IMP) Q06945 (/IMP) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q06831 (/ISO) Q7M6Y2 (/ISO) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q8AXQ4 (/NAS) Q8AXQ4 (/NAS) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q06945 (/TAS) Q06945 (/TAS) |
|
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
2 | P40656 (/IDA) P40656 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
1 | Q7M6Y2 (/ISO) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q06831 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q7M6Y2 (/ISO) |
|
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
1 | Q7M6Y2 (/ISO) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q7M6Y2 (/ISO) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | O57399 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q66JF1 (/ISS) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q06831 (/IDA) |
There are 201 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
|
13 |
D3ZZ13 (/ISS)
E2RH58 (/ISS)
F1RUF9 (/ISS)
F1S9L1 (/ISS)
O15370 (/ISS)
O15370 (/ISS)
P0C1G9 (/ISS)
P35716 (/ISS)
P35716 (/ISS)
Q06945 (/ISS)
(3 more) |
|
Negative regulation of smoothened signaling pathway GO:0045879
Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
|
11 |
A0A0R4IQD2 (/IGI)
Q1RM26 (/IGI)
Q5TZG4 (/IGI)
Q6A3P6 (/IGI)
Q6P0Z4 (/IGI)
Q6P2A2 (/IGI)
Q6UJB6 (/IGI)
Q9I9C7 (/IGI)
Q9I9C8 (/IGI)
Q9YH22 (/IGI)
(1 more) |
|
Closure of optic fissure GO:0061386
The closure of the temporary ventral gap in the optic cup that contributes to its shaping.
|
11 |
A0A0R4IQD2 (/IGI)
Q1RM26 (/IGI)
Q5TZG4 (/IGI)
Q6A3P6 (/IGI)
Q6P0Z4 (/IGI)
Q6P2A2 (/IGI)
Q6UJB6 (/IGI)
Q9I9C7 (/IGI)
Q9I9C8 (/IGI)
Q9YH22 (/IGI)
(1 more) |
|
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Neural tube formation GO:0001841
The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Cardiac ventricle formation GO:0003211
The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Glial cell proliferation GO:0014009
The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Glial cell development GO:0021782
The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
8 | D3ZZ13 (/ISS) E2RH58 (/ISS) F1RUF9 (/ISS) O15370 (/ISS) O15370 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) Q6X895 (/ISS) |
|
Sympathetic nervous system development GO:0048485
The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Limb bud formation GO:0060174
The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Neuroepithelial cell differentiation GO:0060563
The process in which epiblast cells acquire specialized features of neuroepithelial cells.
|
8 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Noradrenergic neuron differentiation GO:0003357
The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.
|
7 | F1RUF9 (/ISS) F1S9L1 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
7 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
7 | P35716 (/IDA) P35716 (/IDA) Q04890 (/IDA) Q06831 (/IDA) Q06945 (/IDA) Q06945 (/IDA) Q7M6Y2 (/IDA) |
|
Lens development in camera-type eye GO:0002088
The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
|
6 | Q1RM26 (/IGI) Q5TZG4 (/IGI) Q9I9C7 (/IGI) Q9I9C8 (/IGI) Q9YH22 (/IGI) Q9YH23 (/IGI) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
6 | Q1RM26 (/IMP) Q5TZG4 (/IMP) Q9I9C7 (/IMP) Q9I9C8 (/IMP) Q9YH22 (/IMP) Q9YH23 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
6 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q0VCF8 (/ISS) |
|
Retinal rod cell development GO:0046548
Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.
|
6 | Q1RM26 (/IGI) Q5TZG4 (/IGI) Q9I9C7 (/IGI) Q9I9C8 (/IGI) Q9YH22 (/IGI) Q9YH23 (/IGI) |
|
Camera-type eye morphogenesis GO:0048593
The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
|
6 | Q1RM26 (/IGI) Q5TZG4 (/IGI) Q9I9C7 (/IGI) Q9I9C8 (/IGI) Q9YH22 (/IGI) Q9YH23 (/IGI) |
|
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
|
6 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) Q06945 (/ISS) Q06945 (/ISS) |
|
Lens morphogenesis in camera-type eye GO:0002089
The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Pro-B cell differentiation GO:0002328
The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
4 | Q06831 (/IMP) Q06945 (/IMP) Q06945 (/IMP) Q7M6Y2 (/IMP) |
|
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Spinal cord motor neuron differentiation GO:0021522
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of BMP signaling pathway GO:0030513
Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Endocrine pancreas development GO:0031018
The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
|
4 | A0A0R4IQD2 (/IMP) Q06831 (/IMP) Q6P2A2 (/IMP) Q6UJB6 (/IMP) |
|
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q06831 (/IDA) Q06945 (/IDA) Q06945 (/IDA) Q7M6Y2 (/IDA) |
|
Positive regulation of hormone secretion GO:0046887
Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Embryonic digestive tract morphogenesis GO:0048557
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Embryonic skeletal system morphogenesis GO:0048704
The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Hard palate development GO:0060022
The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Soft palate development GO:0060023
The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Lung morphogenesis GO:0060425
The process in which the anatomical structures of the lung are generated and organized.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Eyelid development in camera-type eye GO:0061029
The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Somite development GO:0061053
The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Cornea development in camera-type eye GO:0061303
The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Closure of optic fissure GO:0061386
The closure of the temporary ventral gap in the optic cup that contributes to its shaping.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
4 | F1RUF9 (/ISS) Q06945 (/ISS) Q06945 (/ISS) Q0VCF8 (/ISS) |
|
Negative regulation of transcription regulatory region DNA binding GO:2000678
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
|
4 | F1S9L1 (/ISS) P35716 (/ISS) P35716 (/ISS) Q7M6Y2 (/ISS) |
|
Positive regulation of lens epithelial cell proliferation GO:2001111
Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.
|
4 | F1S9L1 (/ISS) P0C1G9 (/ISS) P35716 (/ISS) P35716 (/ISS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
3 | P35716 (/IDA) P35716 (/IDA) Q7M6Y2 (/IDA) |
|
Noradrenergic neuron differentiation GO:0003357
The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.
|
3 | P0C1G9 (/IMP) Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
3 | Q5TZG4 (/IMP) Q9I9C7 (/IMP) Q9YH22 (/IMP) |
|
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
3 | Q5TZG4 (/IDA) Q9I9C7 (/IDA) Q9YH22 (/IDA) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
3 | P35716 (/IMP) P35716 (/IMP) Q7M6Y2 (/IMP) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
3 | P35716 (/IMP) P35716 (/IMP) Q7M6Y2 (/IMP) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
3 | Q5TZG4 (/IMP) Q9I9C7 (/IMP) Q9YH22 (/IMP) |
|
Negative regulation of protein ubiquitination GO:0031397
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
DNA damage response, detection of DNA damage GO:0042769
The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
3 | P35716 (/IMP) P35716 (/IMP) Q7M6Y2 (/IMP) |
|
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
3 | F1S9L1 (/ISS) P0C1G9 (/ISS) Q7M6Y2 (/ISS) |
|
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
3 | P35716 (/IMP) P35716 (/IMP) Q7M6Y2 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | Q06945 (/IMP) Q06945 (/IMP) Q7M6Y2 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | P0C1G9 (/IMP) Q06945 (/IMP) Q06945 (/IMP) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
3 | Q06831 (/IMP) Q06945 (/IMP) Q06945 (/IMP) |
|
Negative regulation of glial cell proliferation GO:0060253
Any process that stops or decreases the rate or extent of glial cell proliferation.
|
3 | P35716 (/IMP) P35716 (/IMP) Q7M6Y2 (/IMP) |
|
Regulation of sprouting angiogenesis GO:1903670
Any process that modulates the frequency, rate or extent of sprouting angiogenesis.
|
3 | Q5TZG4 (/IMP) Q9I9C7 (/IMP) Q9YH22 (/IMP) |
|
Positive regulation of stem cell proliferation GO:2000648
Any process that activates or increases the frequency, rate or extent of stem cell proliferation.
|
3 | F1S9L1 (/ISS) P0C1G9 (/ISS) Q7M6Y2 (/ISS) |
|
Positive regulation of N-terminal peptidyl-lysine acetylation GO:2000761
Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | F1S9L1 (/ISS) P0C1G9 (/ISS) |
|
Skeletal system development GO:0001501
The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Neural tube formation GO:0001841
The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Mitral valve morphogenesis GO:0003183
The process in which the structure of the mitral valve is generated and organized.
|
2 | Q06945 (/ISS) Q06945 (/ISS) |
|
Cardiac ventricle formation GO:0003211
The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Cardiac right ventricle morphogenesis GO:0003215
The process in which the right cardiac ventricle is generated and organized.
|
2 | Q06945 (/ISS) Q06945 (/ISS) |
|
Atrial septum primum morphogenesis GO:0003289
The process in which anatomical structure of an atrial septum primum is generated and organized.
|
2 | Q06945 (/ISS) Q06945 (/ISS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q06945 (/IDA) Q06945 (/IDA) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q8AXQ4 (/NAS) Q8AXQ4 (/NAS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | P40656 (/IMP) P40656 (/IMP) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
2 | O15370 (/NAS) O15370 (/NAS) |
|
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
|
2 | Q06945 (/IMP) Q06945 (/IMP) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
2 | P40650 (/IGI) Q91731 (/IGI) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
2 | P40650 (/IMP) Q91731 (/IMP) |
|
Metamorphosis GO:0007552
A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.
|
2 | P40656 (/IMP) P40656 (/IMP) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
2 | Q06945 (/IMP) Q06945 (/IMP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | F1S9L1 (/ISS) P0C1G9 (/ISS) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | F1S9L1 (/ISS) P0C1G9 (/ISS) |
|
Glial cell proliferation GO:0014009
The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Neuron remodeling GO:0016322
The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
|
2 | P40656 (/IGI) P40656 (/IGI) |
|
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
|
2 | P35716 (/IEP) P35716 (/IEP) |
|
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Glial cell development GO:0021782
The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
2 | P35716 (/IEP) P35716 (/IEP) |
|
Negative regulation of protein ubiquitination GO:0031397
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
2 | Q06945 (/IMP) Q06945 (/IMP) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
2 | Q06945 (/IMP) Q06945 (/IMP) |
|
Ascending aorta morphogenesis GO:0035910
The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
|
2 | Q06945 (/ISS) Q06945 (/ISS) |
|
DNA damage response, detection of DNA damage GO:0042769
The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal.
|
2 | Q06945 (/IDA) Q06945 (/IDA) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
2 | Q06945 (/IMP) Q06945 (/IMP) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
2 | F1RUF9 (/ISS) Q0VCF8 (/ISS) |
|
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
|
2 | O15370 (/IEP) O15370 (/IEP) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
2 | F1S9L1 (/ISS) P0C1G9 (/ISS) |
|
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
2 | P35716 (/IMP) P35716 (/IMP) |
|
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
2 | Q06945 (/IMP) Q06945 (/IMP) |
|
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
2 | F1S9L1 (/ISS) P0C1G9 (/ISS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q06831 (/ISO) Q7M6Y2 (/ISO) |
|
Sympathetic nervous system development GO:0048485
The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
|
2 | P40656 (/IGI) P40656 (/IGI) |
|
Negative regulation of lymphocyte proliferation GO:0050672
Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.
|
2 | P35716 (/IMP) P35716 (/IMP) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
2 | F1RUF9 (/ISS) Q0VCF8 (/ISS) |
|
Limb bud formation GO:0060174
The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Negative regulation of glial cell proliferation GO:0060253
Any process that stops or decreases the rate or extent of glial cell proliferation.
|
2 | F1S9L1 (/ISS) P0C1G9 (/ISS) |
|
Ventricular septum morphogenesis GO:0060412
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Neuroepithelial cell differentiation GO:0060563
The process in which epiblast cells acquire specialized features of neuroepithelial cells.
|
2 | Q06831 (/IMP) Q7M6Y2 (/IMP) |
|
Kidney morphogenesis GO:0060993
Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
|
2 | Q06945 (/ISS) Q06945 (/ISS) |
|
Signal transduction involved in cell cycle checkpoint GO:0072395
A signal transduction process that contributes to a cell cycle checkpoint.
|
2 | P35716 (/IEP) P35716 (/IEP) |
|
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
2 | P48435 (/IDA) Q06831 (/IDA) |
|
Regulation of neuron remodeling GO:1904799
Any process that modulates the frequency, rate or extent of neuron remodeling.
|
2 | P40656 (/IMP) P40656 (/IMP) |
|
Positive regulation of neuron remodeling GO:1904801
Any process that activates or increases the frequency, rate or extent of neuron remodeling.
|
2 | P40656 (/IMP) P40656 (/IMP) |
|
Positive regulation of stem cell proliferation GO:2000648
Any process that activates or increases the frequency, rate or extent of stem cell proliferation.
|
2 | P35716 (/IMP) P35716 (/IMP) |
|
Positive regulation of N-terminal peptidyl-lysine acetylation GO:2000761
Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
|
2 | Q06945 (/IDA) Q06945 (/IDA) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q7M6Y2 (/ISO) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
1 | Q06831 (/ISO) |
|
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
|
1 | P0C1G9 (/IEP) |
|
Lens morphogenesis in camera-type eye GO:0002089
The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
|
1 | Q7M6Y2 (/IMP) |
|
Pro-B cell differentiation GO:0002328
The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
|
1 | Q06831 (/IMP) |
|
Outflow tract morphogenesis GO:0003151
The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
|
1 | Q7M6Y2 (/IMP) |
|
Mitral valve morphogenesis GO:0003183
The process in which the structure of the mitral valve is generated and organized.
|
1 | Q06831 (/IMP) |
|
Cardiac right ventricle morphogenesis GO:0003215
The process in which the right cardiac ventricle is generated and organized.
|
1 | Q06831 (/IMP) |
|
Atrial septum primum morphogenesis GO:0003289
The process in which anatomical structure of an atrial septum primum is generated and organized.
|
1 | Q06831 (/IMP) |
|
Noradrenergic neuron differentiation GO:0003357
The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.
|
1 | Q7M6Y2 (/ISO) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q06831 (/ISO) |
|
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977
A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
|
1 | Q06831 (/ISO) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
1 | Q66JF1 (/ISS) |
|
Mesodermal cell fate specification GO:0007501
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
1 | Q8T3B9 (/IDA) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q06831 (/IMP) |
|
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
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1 | P0C1G9 (/IEP) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
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1 | Q06831 (/ISO) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q06831 (/ISO) |
|
Gene expression GO:0010467
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | O57399 (/IMP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
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1 | Q7M6Y2 (/ISO) |
|
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
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1 | Q7M6Y2 (/ISO) |
|
Oligodendrocyte development GO:0014003
The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.
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1 | P0C1G9 (/IEP) |
|
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
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1 | Q7M6Y2 (/IMP) |
|
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
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1 | Q04890 (/IDA) |
|
Spinal cord motor neuron differentiation GO:0021522
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
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1 | Q06831 (/IMP) |
|
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
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1 | Q06831 (/IMP) |
|
Positive regulation of BMP signaling pathway GO:0030513
Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.
|
1 | Q7M6Y2 (/IMP) |
|
Negative regulation of protein ubiquitination GO:0031397
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.
|
1 | Q06831 (/ISO) |
|
Regulation of protein stability GO:0031647
Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
|
1 | Q06831 (/ISO) |
|
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
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1 | Q06831 (/IMP) |
|
Somatic stem cell population maintenance GO:0035019
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
|
1 | Q06831 (/IDA) |
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Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
|
1 | Q7M6Y2 (/IMP) |
|
Ascending aorta morphogenesis GO:0035910
The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
|
1 | Q06831 (/IMP) |
|
Skeletal muscle cell differentiation GO:0035914
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
|
1 | Q7M6Y2 (/IMP) |
|
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
|
1 | Q8T3B9 (/IMP) |
|
Positive regulation of vulval development GO:0040026
Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
1 | Q8T3B9 (/IMP) |
|
Glucose homeostasis GO:0042593
Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
|
1 | Q06831 (/IMP) |
|
DNA damage response, detection of DNA damage GO:0042769
The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal.
|
1 | Q06831 (/ISO) |
|
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q06831 (/ISO) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
1 | Q7M6Y2 (/IDA) |
|
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
1 | Q7M6Y2 (/ISO) |
|
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
1 | Q7M6Y2 (/ISO) |
|
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
1 | Q06831 (/ISO) |
|
Positive regulation of ossification GO:0045778
Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
|
1 | Q7M6Y2 (/ISO) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q06831 (/ISO) |
|
Positive regulation of hormone secretion GO:0046887
Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.
|
1 | Q7M6Y2 (/IMP) |
|
Embryonic eye morphogenesis GO:0048048
The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.
|
1 | Q9DG48 (/IMP) |
|
Positive regulation of mesodermal cell fate specification GO:0048337
Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.
|
1 | Q8T3B9 (/IGI) |
|
Positive regulation of mesodermal cell fate specification GO:0048337
Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.
|
1 | Q8T3B9 (/IMP) |
|
Embryonic digestive tract morphogenesis GO:0048557
The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
|
1 | Q7M6Y2 (/IMP) |
|
Positive regulation of post-embryonic development GO:0048582
Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
|
1 | Q8T3B9 (/IMP) |
|
Myoblast fate specification GO:0048626
The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
1 | Q8T3B9 (/IMP) |
|
Embryonic skeletal system morphogenesis GO:0048704
The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.
|
1 | Q7M6Y2 (/IMP) |
|
Negative regulation of lymphocyte proliferation GO:0050672
Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.
|
1 | Q7M6Y2 (/ISO) |
|
Positive regulation of neurogenesis GO:0050769
Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.
|
1 | Q7M6Y2 (/IDA) |
|
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
|
1 | Q06831 (/ISO) |
|
Hard palate development GO:0060022
The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.
|
1 | Q7M6Y2 (/IMP) |
|
Soft palate development GO:0060023
The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.
|
1 | Q7M6Y2 (/IMP) |
|
Negative regulation of glial cell proliferation GO:0060253
Any process that stops or decreases the rate or extent of glial cell proliferation.
|
1 | Q7M6Y2 (/ISO) |
|
Lung morphogenesis GO:0060425
The process in which the anatomical structures of the lung are generated and organized.
|
1 | Q7M6Y2 (/IMP) |
|
Kidney morphogenesis GO:0060993
Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
|
1 | Q06831 (/IMP) |
|
Eyelid development in camera-type eye GO:0061029
The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.
|
1 | Q7M6Y2 (/IMP) |
|
Somite development GO:0061053
The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
1 | Q7M6Y2 (/IMP) |
|
Cornea development in camera-type eye GO:0061303
The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.
|
1 | Q7M6Y2 (/IMP) |
|
Closure of optic fissure GO:0061386
The closure of the temporary ventral gap in the optic cup that contributes to its shaping.
|
1 | Q7M6Y2 (/IMP) |
|
Protein-DNA complex assembly GO:0065004
The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.
|
1 | Q04890 (/IDA) |
|
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
1 | Q06831 (/IMP) |
|
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | Q06831 (/IMP) |
|
Positive regulation of oviposition GO:1901046
Any process that activates or increases the frequency, rate or extent of oviposition.
|
1 | Q8T3B9 (/IMP) |
|
Positive regulation of stem cell proliferation GO:2000648
Any process that activates or increases the frequency, rate or extent of stem cell proliferation.
|
1 | Q7M6Y2 (/ISO) |
|
Negative regulation of transcription regulatory region DNA binding GO:2000678
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
|
1 | P0C1G9 (/IMP) |
|
Negative regulation of transcription regulatory region DNA binding GO:2000678
Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
|
1 | Q7M6Y2 (/ISO) |
|
Positive regulation of N-terminal peptidyl-lysine acetylation GO:2000761
Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
|
1 | Q06831 (/ISO) |
|
Positive regulation of lens epithelial cell proliferation GO:2001111
Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.
|
1 | Q7M6Y2 (/IMP) |
There are 16 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | P0C1G9 (/IDA) P35716 (/IDA) P35716 (/IDA) Q06831 (/IDA) Q06945 (/IDA) Q06945 (/IDA) Q7M6Y2 (/IDA) Q8T3B9 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | F1RUF9 (/ISS) F1S9L1 (/ISS) P0C1G9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) Q7M6Y2 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P40650 (/IC) Q8AXQ4 (/IC) Q8AXQ4 (/IC) Q91731 (/IC) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | F1RUF9 (/ISS) F1S9L1 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | O15370 (/IDA) O15370 (/IDA) Q06945 (/IDA) Q06945 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | P35716 (/IDA) P35716 (/IDA) Q06945 (/IDA) Q06945 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
3 | F1RUF9 (/ISS) Q06831 (/ISS) Q0VCF8 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P40656 (/IMP) P40656 (/IMP) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q06831 (/ISO) Q7M6Y2 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q04890 (/ISO) Q06831 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | Q06945 (/TAS) Q06945 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q06831 (/ISO) Q7M6Y2 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q06945 (/IDA) Q06945 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q06831 (/ISO) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
1 | Q04890 (/IDA) |
|
Nuclear transcription factor complex GO:0044798
A protein complex, located in the nucleus, that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
1 | Q06831 (/IDA) |