The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"High mobility group box domain
".
FunFam 37: High mobility group protein B2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
33 |
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
(23 more) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
15 |
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
(5 more) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | P87057 (/ISM) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
33 |
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
Q8I616 (/TAS)
(23 more) |
|
Positive regulation of cytokine production GO:0001819
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
|
18 |
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
(8 more) |
|
Positive regulation of cytokine production involved in immune response GO:0002720
Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.
|
15 |
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
Q8IB14 (/IDA)
(5 more) |
|
Regulation of transcription by RNA polymerase III GO:0006359
Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.
|
15 |
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
Q8IB14 (/ISS)
(5 more) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
1 | P87057 (/ISO) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | P87057 (/ISO) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P87057 (/ISO) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
|
33 |
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
(23 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
33 |
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
(23 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
18 |
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
Q8I616 (/IDA)
(8 more) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | P87057 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P87057 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P87057 (/HDA) |