The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"High mobility group box domain
".
FunFam 31: High mobility group protein 20A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
9 | Q9NP66 (/ISA) Q9NP66 (/ISA) Q9NP66 (/ISA) Q9NP66 (/ISA) Q9NP66 (/ISA) Q9NP66 (/ISA) Q9NP66 (/ISA) Q9NP66 (/ISA) Q9NP66 (/ISA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
9 | Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
9 | Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
9 | Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) Q9NP66 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9DC33 (/ISO) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q9DC33 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
|
9 | Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
9 | Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q9DC33 (/IMP) |
|
Negative regulation of protein sumoylation GO:0033234
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
|
1 | Q9DC33 (/IMP) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | Q9DC33 (/IDA) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | Q9DC33 (/IGI) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
9 | Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) Q9NP66 (/NAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9DC33 (/IDA) |