The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial import inner membrane translocase subunit tim13 like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: mitochondrial import inner membrane translocase su...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
11 Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI)
Protein transporter activity GO:0140318
Directly binding to a specific protein and delivering it to a specific cellular location.
7 P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA)
Protein transporter activity GO:0140318
Directly binding to a specific protein and delivering it to a specific cellular location.
7 P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q9XH48 (/IDA) Q9XH48 (/IDA)
P-P-bond-hydrolysis-driven protein transmembrane transporter activity GO:0015450
Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.
2 Q9VTN3 (/ISS) Q9VTN3 (/ISS)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
11 Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS)
(1 more)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
11 Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS)
(1 more)
Chaperone-mediated protein transport GO:0072321
The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.
11 Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS)
(1 more)
Protein insertion into mitochondrial inner membrane GO:0045039
The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.
7 P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA)
Protein insertion into mitochondrial inner membrane GO:0045039
The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.
7 P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP) P53299 (/IMP)
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
2 Q9VTN3 (/ISS) Q9VTN3 (/ISS)
Protein insertion into mitochondrial inner membrane GO:0045039
The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.
1 Q10481 (/ISO)
Protein insertion into mitochondrial inner membrane GO:0045039
The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.
1 Q0E8V7 (/ISS)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
18 K7EIT2 (/IDA) K7EIT2 (/IDA) K7EIT2 (/IDA) P62076 (/IDA) P62076 (/IDA) Q9XH48 (/IDA) Q9XH48 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA)
(8 more)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
14 K7EIT2 (/IDA) K7EIT2 (/IDA) K7EIT2 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA)
(4 more)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
11 Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA) Q9Y5L4 (/IDA)
(1 more)
Mitochondrial intermembrane space protein transporter complex GO:0042719
Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.
11 Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS) Q9Y5L4 (/TAS)
(1 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 P53299 (/HDA) P53299 (/HDA) P53299 (/HDA) P53299 (/HDA) P53299 (/HDA) P53299 (/HDA) P53299 (/HDA) P62075 (/HDA) P62075 (/HDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
9 P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) Q9XH48 (/IDA) Q9XH48 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
7 P53299 (/TAS) P53299 (/TAS) P53299 (/TAS) P53299 (/TAS) P53299 (/TAS) P53299 (/TAS) P53299 (/TAS)
Mitochondrial intermembrane space protein transporter complex GO:0042719
Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.
7 P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA) P53299 (/IDA)
Mitochondrial intermembrane space protein transporter complex GO:0042719
Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.
7 P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI) P53299 (/IPI)
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
2 P62075 (/ISO) P62075 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P62075 (/ISO) P62075 (/ISO)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 P62075 (/ISO) P62075 (/ISO)
TIM23 mitochondrial import inner membrane translocase complex GO:0005744
The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
2 Q9VTN3 (/ISS) Q9VTN3 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q10481 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q0E8V7 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q10481 (/HDA)
Mitochondrial intermembrane space protein transporter complex GO:0042719
Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.
1 Q10481 (/ISO)
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