The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 367: Cyclic nucleotide-gated cation channel

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intracellular cAMP-activated cation channel activity GO:0005222
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.
1 Q03611 (/IDA)
Intracellular cGMP-activated cation channel activity GO:0005223
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.
1 Q03611 (/IDA)
CGMP binding GO:0030553
Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
1 Q03611 (/NAS)

There are 25 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Detection of carbon dioxide GO:0003031
The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.
1 Q03611 (/IMP)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 Q03611 (/IMP)
G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger GO:0007199
The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).
1 Q03611 (/IMP)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
1 Q03611 (/IMP)
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
1 Q03611 (/IMP)
Aerotaxis GO:0009454
The directed movement of a motile cell or organism in response to environmental oxygen.
1 Q03611 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q03611 (/IMP)
Negative regulation of cGMP-mediated signaling GO:0010754
Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
1 Q03611 (/IMP)
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
1 Q03611 (/IMP)
Regulation of axon extension GO:0030516
Any process that modulates the rate, direction or extent of axon extension.
1 Q03611 (/IMP)
Positive regulation of growth rate GO:0040010
Any process that increases the rate of growth of all or part of an organism.
1 Q03611 (/IGI)
Thermosensory behavior GO:0040040
Behavior that is dependent upon the sensation of temperature.
1 Q03611 (/IGI)
Thermosensory behavior GO:0040040
Behavior that is dependent upon the sensation of temperature.
1 Q03611 (/IMP)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q03611 (/IGI)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q03611 (/IMP)
Thermotaxis GO:0043052
The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
1 Q03611 (/IGI)
Thermotaxis GO:0043052
The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
1 Q03611 (/IMP)
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
1 Q03611 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q03611 (/IMP)
Multicellular organismal reproductive process GO:0048609
The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.
1 Q03611 (/IGI)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
1 Q03611 (/IMP)
Detection of chemical stimulus involved in sensory perception GO:0050907
The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.
1 Q03611 (/IMP)
Response to hyperoxia GO:0055093
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
1 Q03611 (/IMP)
Response to oxygen levels GO:0070482
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
1 Q03611 (/IMP)
Cation transmembrane transport GO:0098655
The process in which a cation is transported across a membrane.
1 Q03611 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q03611 (/NAS)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q03611 (/IDA)
Cation channel complex GO:0034703
An ion channel complex through which cations pass.
1 Q03611 (/IDA)
Ciliary inversin compartment GO:0097543
Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium.
1 Q03611 (/IDA)
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
1 Q03611 (/IDA)
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