The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Helix hairpin bin
".
FunFam 3: Cyclic nucleotide-gated ion channel 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
4 | O65718 (/IDA) Q8RWS9 (/IDA) Q8RWS9 (/IDA) Q9LEQ3 (/IDA) |
|
Intracellular cGMP-activated cation channel activity GO:0005223
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.
|
3 | O82226 (/IDA) Q8RWS9 (/IDA) Q8RWS9 (/IDA) |
|
Cation transmembrane transporter activity GO:0008324
Enables the transfer of cation from one side of a membrane to the other.
|
2 | Q94AS9 (/IDA) Q94AS9 (/IDA) |
|
Intracellular cyclic nucleotide activated cation channel activity GO:0005221
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
|
1 | O65718 (/IMP) |
|
Intracellular cAMP-activated cation channel activity GO:0005222
Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.
|
1 | O65718 (/IDA) |
|
Inward rectifier potassium channel activity GO:0005242
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
|
1 | O65718 (/IGI) |
|
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | O65718 (/IMP) |
|
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
1 | O65718 (/TAS) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plant-type hypersensitive response GO:0009626
The rapid, localized death of plant cells in response to invasion by a pathogen.
|
3 | O65718 (/IMP) Q94AS9 (/IMP) Q94AS9 (/IMP) |
|
Pollen tube growth GO:0009860
Growth of pollen via tip extension of the intine wall.
|
2 | Q9FXH6 (/IGI) Q9S9N5 (/IGI) |
|
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
2 | O82226 (/IEP) Q9S9N5 (/IEP) |
|
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
|
1 | Q9LEQ3 (/IDA) |
|
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
|
1 | O65718 (/TAS) |
|
Nitric oxide mediated signal transduction GO:0007263
Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.
|
1 | O65718 (/IMP) |
|
Response to nematode GO:0009624
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
|
1 | Q9LD37 (/IEP) |
|
Pollen tube growth GO:0009860
Growth of pollen via tip extension of the intine wall.
|
1 | Q9LEQ3 (/IMP) |
|
Calcium ion import GO:0070509
The directed movement of calcium ions into a cell or organelle.
|
1 | O65718 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | O65717 (/IDA) O82226 (/IDA) Q8RWS9 (/IDA) Q8RWS9 (/IDA) Q9S9N5 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
5 | Q8RWS9 (/IDA) Q8RWS9 (/IDA) Q94AS9 (/IDA) Q94AS9 (/IDA) Q9M0A4 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q9LEQ3 (/IDA) |
|
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
|
1 | O82226 (/IDA) |
|
Pollen tube GO:0090406
A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.
|
1 | Q9S9N5 (/IDA) |
