CATH Superfamily 1.10.287.370
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: Probable prefoldin subunit 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
17 |
B5DFN4 (/IPI)
O94307 (/IPI)
Q04493 (/IPI)
Q04493 (/IPI)
Q04493 (/IPI)
Q04493 (/IPI)
Q04493 (/IPI)
Q99471 (/IPI)
Q99471 (/IPI)
Q99471 (/IPI)
(7 more) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
10 | Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) |
|
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
|
5 | Q04493 (/IDA) Q04493 (/IDA) Q04493 (/IDA) Q04493 (/IDA) Q04493 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
10 | Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
10 | Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) |
|
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
10 | Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) Q99471 (/IMP) |
|
Tubulin complex assembly GO:0007021
The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.
|
5 | Q04493 (/IMP) Q04493 (/IMP) Q04493 (/IMP) Q04493 (/IMP) Q04493 (/IMP) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
5 | Q04493 (/IGI) Q04493 (/IGI) Q04493 (/IGI) Q04493 (/IGI) Q04493 (/IGI) |
|
Positive regulation of transcription elongation from RNA polymerase II promoter GO:0032968
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
|
5 | Q04493 (/IMP) Q04493 (/IMP) Q04493 (/IMP) Q04493 (/IMP) Q04493 (/IMP) |
|
Tubulin complex assembly GO:0007021
The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.
|
1 | O94307 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9WU28 (/ISO) |
|
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
|
1 | Q9WU28 (/IMP) |
|
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | Q9WU28 (/ISO) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
10 | Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
10 | Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) Q99471 (/TAS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | Q04493 (/IC) Q04493 (/IC) Q04493 (/IC) Q04493 (/IC) Q04493 (/IC) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | Q04493 (/IDA) Q04493 (/IDA) Q04493 (/IDA) Q04493 (/IDA) Q04493 (/IDA) |
|
Prefoldin complex GO:0016272
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
|
5 | Q04493 (/IPI) Q04493 (/IPI) Q04493 (/IPI) Q04493 (/IPI) Q04493 (/IPI) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q8HYI9 (/TAS) Q8HYI9 (/TAS) Q8HYI9 (/TAS) |
|
Prefoldin complex GO:0016272
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
|
2 | Q9VCZ8 (/IDA) Q9VCZ8 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O94307 (/HDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O94307 (/HDA) |
|
Prefoldin complex GO:0016272
A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
|
1 | O94307 (/ISS) |
|
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | O94307 (/IDA) |
|
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
|
1 | O94307 (/IDA) |
