CATH Superfamily 1.10.287.130
Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 8: Two-component sensor histidine kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphorelay sensor kinase activity GO:0000155
Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
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2 | Q83EF7 (/ISS) Q83EF7 (/ISS) |
|
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
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2 | Q83EF7 (/ISS) Q83EF7 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
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2 | Q9WZV7 (/IPI) Q9WZV7 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
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2 | Q9WZV7 (/IPI) Q9WZV7 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
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8 | P9WGK5 (/IMP) P9WGK5 (/IMP) P9WGK5 (/IMP) P9WGK5 (/IMP) P9WGK5 (/IMP) P9WGK5 (/IMP) P9WGK5 (/IMP) P9WGK5 (/IMP) |
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Peptidyl-histidine phosphorylation GO:0018106
The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).
|
8 | P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) |
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Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
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8 | P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) P9WGK5 (/IDA) |
|
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
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2 | Q83EF7 (/ISS) Q83EF7 (/ISS) |
|
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
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2 | Q83EF7 (/ISS) Q83EF7 (/ISS) |
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Phosphate ion transport GO:0006817
The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
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2 | Q83EF7 (/ISS) Q83EF7 (/ISS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
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8 | P9WGK5 (/HDA) P9WGK5 (/HDA) P9WGK5 (/HDA) P9WGK5 (/HDA) P9WGK5 (/HDA) P9WGK5 (/HDA) P9WGK5 (/HDA) P9WGK5 (/HDA) |
