The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
MazG-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Nucleoside triphosphate pyrophosphohydrolase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
104 P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI) P0AEY3 (/IPI)
(94 more)
Nucleoside-triphosphate diphosphatase activity GO:0047429
Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
104 P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA) P0AEY3 (/IDA)
(94 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity GO:0035539
Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
ATP diphosphatase activity GO:0047693
Catalysis of the reaction: ATP + H2O = AMP + diphosphate.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
104 P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP) P0AEY3 (/IMP)
(94 more)
DGTP catabolic process GO:0006203
The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
TTP catabolic process GO:0046047
The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
UTP catabolic process GO:0046052
The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
DATP catabolic process GO:0046061
The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
DTTP catabolic process GO:0046076
The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
DUTP catabolic process GO:0046081
The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.
6 P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA) P96379 (/IDA)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
6 P96379 (/IPI) P96379 (/IPI) P96379 (/IPI) P96379 (/IPI) P96379 (/IPI) P96379 (/IPI)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
6 P96379 (/HDA) P96379 (/HDA) P96379 (/HDA) P96379 (/HDA) P96379 (/HDA) P96379 (/HDA)