The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ESAT-6-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Charged multivesicular body protein 7

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 O94318 (/IPI) Q9P7F7 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Late endosome to vacuole transport GO:0045324
The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
3 Q5FW14 (/ISS) Q5ZJB7 (/ISS) Q86H98 (/ISS)
Exit from mitosis GO:0010458
The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
2 Q5FW14 (/ISS) Q5ZJB7 (/ISS)
Nuclear envelope reassembly GO:0031468
The reformation of the nuclear envelope following its breakdown in the context of a normal process.
2 Q5FW14 (/ISS) Q5ZJB7 (/ISS)
Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043328
The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.
2 O94318 (/IMP) Q9P7F7 (/IMP)
Late endosome to vacuole transport GO:0045324
The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
2 O94318 (/IMP) Q9P7F7 (/IMP)
Regulation of receptor recycling GO:0001919
Any process that modulates the frequency, rate, or extent of receptor recycling.
1 Q86H98 (/IMP)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
1 Q86H98 (/IMP)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
1 Q86H98 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ESCRT III complex GO:0000815
An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes.
3 Q5FW14 (/ISS) Q5ZJB7 (/ISS) Q86H98 (/ISS)
ESCRT III complex GO:0000815
An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes.
2 O94318 (/ISO) Q9P7F7 (/ISO)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
2 Q5FW14 (/ISS) Q5ZJB7 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q86H98 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9P7F7 (/HDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
1 Q86H98 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 O94318 (/HDA)
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