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CATH Superfamily 1.10.260.40

lambda repressor-like DNA-binding domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
lambda repressor-like DNA-binding domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 82: (S)-2-hydroxypropylphosphonic acid epoxidase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(S)-2-hydroxypropylphosphonic acid epoxidase. [EC: 1.11.1.23]
(S)-2-hydroxypropylphosphonate + H(2)O(2) = (1R,2S)-1,2- epoxypropylphosphonate + 2 H(2)O.
  • This is the last enzyme in the biosynthetic pathway of fosfomycin, a broad-spectrum antibiotic produced by certain Streptomyces species.
  • Contains non heme iron that forms a iron(IV)-oxo (ferryl) complex with hydrogen peroxide, which functions as a proton abstractor from the substrate.
  • Formerly EC 1.14.19.7.
 4 A0A0L8KLT8 A0A0L8KLT8 Q56185 Q56185