The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
lambda repressor-like DNA-binding domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 53: Transcriptional regulator

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Toxin-antitoxin pair type II binding GO:0097351
Interacting selectively and non-covalently with a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other.
13 P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI) P9WJA7 (/IPI)
(3 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
13 P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP) P9WJA7 (/IEP)
(3 more)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
13 P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA) P9WJA7 (/IDA)
(3 more)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
13 P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP)
(3 more)
Positive regulation of growth GO:0045927
Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
13 P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP) P9WJA7 (/IMP)
(3 more)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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