The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"lambda repressor-like DNA-binding domains
".
FunFam 11: homeobox-containing protein 1 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
24 |
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
(14 more) |
|
Telomeric DNA binding GO:0042162
Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
|
24 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(14 more) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
24 |
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
(14 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
23 |
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
Q6NT76 (/ISA)
(13 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
23 |
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
Q6NT76 (/ISM)
(13 more) |
|
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
23 |
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
Q6NT76 (/IC)
(13 more) |
|
Double-stranded telomeric DNA binding GO:0003691
Interacting selectively and non-covalently with double-stranded telomere-associated DNA.
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Telomeric DNA binding GO:0042162
Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
|
23 |
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
(13 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
23 |
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
Q6NT76 (/IPI)
(13 more) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Double-stranded telomeric DNA binding GO:0003691
Interacting selectively and non-covalently with double-stranded telomere-associated DNA.
|
1 | Q8BJA3 (/ISO) |
|
Telomeric DNA binding GO:0042162
Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
|
1 | Q8BJA3 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q8BJA3 (/ISO) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q8BJA3 (/ISO) |
|
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
|
1 | Q8BJA3 (/ISO) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
23 |
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
(13 more) |
|
Positive regulation of chromatin binding GO:0035563
Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
23 |
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
Q6NT76 (/ISS)
(13 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Regulation of telomerase activity GO:0051972
Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
23 |
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
Q6NT76 (/IMP)
(13 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | Q8BJA3 (/ISO) |
|
Positive regulation of telomere maintenance via telomerase GO:0032212
Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
|
1 | Q8BJA3 (/ISO) |
|
Positive regulation of chromatin binding GO:0035563
Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q8BJA3 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8BJA3 (/ISO) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q8BJA3 (/ISS) |
|
Regulation of telomerase activity GO:0051972
Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
|
1 | Q8BJA3 (/ISO) |
|
Positive regulation of telomerase activity GO:0051973
Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
|
1 | Q8BJA3 (/ISO) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
32 |
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
H0YKJ1 (/IDA)
H0YKJ1 (/IDA)
H0YLF2 (/IDA)
Q6NT76 (/IDA)
(22 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
32 |
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
H0YKJ1 (/IDA)
H0YKJ1 (/IDA)
H0YLF2 (/IDA)
Q6NT76 (/IDA)
(22 more) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
32 |
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
E5RGZ2 (/IDA)
H0YKJ1 (/IDA)
H0YKJ1 (/IDA)
H0YLF2 (/IDA)
Q6NT76 (/IDA)
(22 more) |
|
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
|
24 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(14 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
24 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(14 more) |
|
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
|
23 |
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
Q6NT76 (/HDA)
(13 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
23 |
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
Q6NT76 (/IDA)
(13 more) |
|
Nuclear chromosome, telomeric region GO:0000784
The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
|
1 | Q8BJA3 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8BJA3 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8BJA3 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8BJA3 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8BJA3 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8BJA3 (/ISS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8BJA3 (/ISO) |
|
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
|
1 | Q8BJA3 (/ISO) |
