The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Eukaryotic translation initiation factor 3 like domains
".
FunFam 4: Eukaryotic translation initiation factor 3 subunit...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
|
7 | Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) |
|
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
|
7 | Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) |
|
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
|
3 | Q5ACM9 (/NAS) Q5ACM9 (/NAS) Q5ACM9 (/NAS) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000462
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
|
7 | Q05775 (/IMP) Q05775 (/IMP) Q05775 (/IMP) Q05775 (/IMP) Q05775 (/IMP) Q05775 (/IMP) Q05775 (/IMP) |
|
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
|
7 | Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) |
|
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
|
7 | Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) Q05775 (/ISS) |
|
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
|
3 | Q5ACM9 (/NAS) Q5ACM9 (/NAS) Q5ACM9 (/NAS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Eukaryotic translation initiation factor 3 complex GO:0005852
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
|
7 | Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) Q05775 (/IPI) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
7 | Q05775 (/IDA) Q05775 (/IDA) Q05775 (/IDA) Q05775 (/IDA) Q05775 (/IDA) Q05775 (/IDA) Q05775 (/IDA) |
