The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Enhancer of yellow 2 transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin insulator sequence binding GO:0043035
Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
11 B3MQ24 (/ISS) B3NUB6 (/ISS) B4H2S0 (/ISS) B4IK33 (/ISS) B4JLC3 (/ISS) B4L1Z8 (/ISS) B4M6M6 (/ISS) B4N1G8 (/ISS) B4NUB3 (/ISS) B4PY93 (/ISS)
(1 more)
TFIID-class transcription factor complex binding GO:0001094
Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
2 Q9VYX1 (/IPI) Q9VYX1 (/IPI)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9VYX1 (/IPI) Q9VYX1 (/IPI)
Chromatin insulator sequence binding GO:0043035
Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
C2H2 zinc finger domain binding GO:0070742
Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
2 Q9VYX1 (/IPI) Q9VYX1 (/IPI)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
11 B3MQ24 (/ISS) B3NUB6 (/ISS) B4H2S0 (/ISS) B4IK33 (/ISS) B4JLC3 (/ISS) B4L1Z8 (/ISS) B4M6M6 (/ISS) B4N1G8 (/ISS) B4NUB3 (/ISS) B4PY93 (/ISS)
(1 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
11 B3MQ24 (/ISS) B3NUB6 (/ISS) B4H2S0 (/ISS) B4IK33 (/ISS) B4JLC3 (/ISS) B4L1Z8 (/ISS) B4M6M6 (/ISS) B4N1G8 (/ISS) B4NUB3 (/ISS) B4PY93 (/ISS)
(1 more)
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
2 Q9VYX1 (/IMP) Q9VYX1 (/IMP)
Histone deubiquitination GO:0016578
The modification of histones by removal of ubiquitin groups.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
Poly(A)+ mRNA export from nucleus GO:0016973
The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
2 Q9VYX1 (/IMP) Q9VYX1 (/IMP)
Negative regulation of chromatin silencing GO:0031936
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.
2 Q9VYX1 (/IMP) Q9VYX1 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9VYX1 (/IMP) Q9VYX1 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q9VYX1 (/IMP) Q9VYX1 (/IMP)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SAGA complex GO:0000124
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8.
11 B3MQ24 (/ISS) B3NUB6 (/ISS) B4H2S0 (/ISS) B4IK33 (/ISS) B4JLC3 (/ISS) B4L1Z8 (/ISS) B4M6M6 (/ISS) B4N1G8 (/ISS) B4NUB3 (/ISS) B4PY93 (/ISS)
(1 more)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
11 B3MQ24 (/ISS) B3NUB6 (/ISS) B4H2S0 (/ISS) B4IK33 (/ISS) B4JLC3 (/ISS) B4L1Z8 (/ISS) B4M6M6 (/ISS) B4N1G8 (/ISS) B4NUB3 (/ISS) B4PY93 (/ISS)
(1 more)
SAGA complex GO:0000124
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
SAGA complex GO:0000124
A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery; the ubiquitin specifc protease Ubp-8.
2 Q9VYX1 (/IPI) Q9VYX1 (/IPI)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
Transcription export complex 2 GO:0070390
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
DUBm complex GO:0071819
A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.
2 Q9VYX1 (/IDA) Q9VYX1 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...