CATH Superfamily 1.10.246.130
Gamma-glutamyltranspeptidase, large (L) subunit, C-terminal domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: Gamma-glutamyltranspeptidase (Ggt)
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Gamma-glutamyl-peptidase activity GO:0034722
Catalysis of the cleavage of a gamma-linked glutamate bond.
|
5 | P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) |
|
Glutathione hydrolase activity GO:0036374
Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate.
|
5 | P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Amino acid salvage GO:0043102
Any process which produces an amino acid from derivatives of it, without de novo synthesis.
|
5 | P18956 (/IMP) P18956 (/IMP) P18956 (/IMP) P18956 (/IMP) P18956 (/IMP) |
|
Self proteolysis GO:0097264
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
|
5 | P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) |
|
Positive regulation of interleukin-8 production GO:0032757
Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.
|
3 | O25743 (/IMP) O25743 (/IMP) O25743 (/IMP) |
|
Negative regulation of T cell proliferation GO:0042130
Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
|
3 | O25743 (/IMP) O25743 (/IMP) O25743 (/IMP) |
|
Negative regulation of cell cycle G1/S phase transition GO:1902807
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.
|
3 | O25743 (/IDA) O25743 (/IDA) O25743 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
|
5 | P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) |
|
Periplasmic space GO:0042597
The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
|
5 | P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) P18956 (/IDA) |
