The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial ATP synthase-coupling factor 6
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: ATP synthase-coupling factor 6, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transmembrane transporter activity GO:0022857
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
2 P18859 (/IC) P18859 (/IC)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 P21571 (/IDA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 P97450 (/ISO)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
3 Q24407 (/ISS) Q24407 (/ISS) Q24407 (/ISS)
ATP biosynthetic process GO:0006754
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
2 P18859 (/TAS) P18859 (/TAS)
Substantia nigra development GO:0021762
The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).
2 P18859 (/HEP) P18859 (/HEP)
Cristae formation GO:0042407
The assembly of cristae, the inwards folds of the inner mitochondrial membrane.
2 P18859 (/TAS) P18859 (/TAS)
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
2 P18859 (/IC) P18859 (/IC)
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
2 P18859 (/TAS) P18859 (/TAS)
Positive regulation of heart rate GO:0010460
Any process that activates or increases the frequency or rate of heart contraction.
1 P21571 (/IDA)
Positive regulation of heart rate GO:0010460
Any process that activates or increases the frequency or rate of heart contraction.
1 P97450 (/ISO)
Response to muscle activity GO:0014850
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
1 P21571 (/IEP)
Negative regulation of prostaglandin secretion GO:0032307
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
1 P21571 (/IDA)
Negative regulation of prostaglandin secretion GO:0032307
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
1 P21571 (/IMP)
Negative regulation of prostaglandin secretion GO:0032307
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
1 P97450 (/ISO)
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
1 P21571 (/IDA)
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
1 P21571 (/IMP)
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
1 P97450 (/ISO)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
1 P21571 (/IDA)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
1 P97450 (/ISO)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
1 Q9VZ72 (/ISS)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 C1BG59 (/IDA)
Negative regulation of arachidonic acid secretion GO:1900139
Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.
1 P21571 (/IDA)
Negative regulation of arachidonic acid secretion GO:1900139
Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.
1 P97450 (/ISO)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
7 P13618 (/ISS) P97450 (/ISS) Q5RBY3 (/ISS) Q5RBY3 (/ISS) Q8SPH6 (/ISS) Q8SPH6 (/ISS) Q8SPH6 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 P18859 (/HDA) P18859 (/HDA) P97450 (/HDA) Q24407 (/HDA) Q24407 (/HDA) Q24407 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 A8MUH2 (/IDA) P18859 (/IDA) P18859 (/IDA) P21571 (/IDA) Q6IB54 (/IDA) Q6IB54 (/IDA)
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
5 P02721 (/IDA) P02721 (/IDA) P18859 (/IDA) P18859 (/IDA) P21571 (/IDA)
Mitochondrial proton-transporting ATP synthase, central stalk GO:0005756
One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.
3 Q24407 (/ISS) Q24407 (/ISS) Q24407 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P18859 (/TAS) P18859 (/TAS)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 P18859 (/TAS) P18859 (/TAS)
Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276
All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.
1 P21571 (/IDA)
Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276
All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.
1 P97450 (/ISO)
Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276
All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.
1 Q9VZ72 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P21571 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P97450 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P97450 (/ISO)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 P97450 (/HDA)
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
1 P97450 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P21571 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P97450 (/ISO)