CATH Superfamily 1.10.238.230
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 1: Serine/threonine-protein phosphatase 2A regulatory...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | Q06190 (/IPI) Q9Y5P8 (/IPI) Q9Z176 (/IPI) |
Protein phosphatase regulator activity GO:0019888
Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
|
2 | Q06190 (/TAS) Q9Y5P8 (/TAS) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q9Z176 (/IDA) |
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
|
1 | Q9Y5P8 (/ISS) |
Calcium-dependent protein serine/threonine phosphatase activity GO:0004723
Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.
|
1 | Q9Z176 (/IDA) |
Protein phosphatase regulator activity GO:0019888
Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
|
1 | Q9Z176 (/IDA) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Eye photoreceptor cell differentiation GO:0001754
The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Somatic muscle development GO:0007525
The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Negative regulation of canonical Wnt signaling pathway GO:0090090
Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Regulation of cell motility involved in somitogenic axis elongation GO:0090249
Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
3 | B0S5Q0 (/IMP) B0S5Q1 (/IMP) E9QG28 (/IMP) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
2 | Q06190 (/ISS) Q9Y5P8 (/ISS) |
Eye photoreceptor cell differentiation GO:0001754
The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.
|
1 | F6T226 (/IMP) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q9Z176 (/IDA) |
Cell cycle arrest GO:0007050
A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
|
1 | Q9Y5P8 (/TAS) |
Somatic muscle development GO:0007525
The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
|
1 | F6T226 (/IMP) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q9Z176 (/IDA) |
Post-anal tail morphogenesis GO:0036342
The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.
|
1 | F6T226 (/IMP) |
Regulation of canonical Wnt signaling pathway GO:0060828
Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | F6T226 (/IGI) |
Somite development GO:0061053
The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
1 | F6T226 (/IMP) |
Somite development GO:0061053
The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
1 | Q06190 (/ISS) |
Wnt signaling pathway involved in somitogenesis GO:0090244
The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.
|
1 | F6T226 (/IC) |
Regulation of cell motility involved in somitogenic axis elongation GO:0090249
Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.
|
1 | F6T226 (/IMP) |
Positive regulation of canonical Wnt signaling pathway GO:0090263
Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | F6T226 (/IMP) |
Negative regulation of G1/S transition of mitotic cell cycle GO:2000134
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
|
1 | Q9Z176 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein phosphatase type 2A complex GO:0000159
A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
|
4 | B2RXC8 (/ISO) G3X9E8 (/ISO) Q3V1Y6 (/ISO) Q8BM38 (/ISO) |
Protein phosphatase type 2A complex GO:0000159
A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
|
2 | Q06190 (/IDA) Q9Z176 (/IDA) |
Protein phosphatase type 2A complex GO:0000159
A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
|
2 | Q06190 (/ISS) Q9Y5P8 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9Y5P8 (/TAS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9Y5P8 (/TAS) |