The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 82: Myosin light chain 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
20 |
O14008 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
(10 more) |
Myosin binding GO:0017022
Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
|
9 | P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) |
Myosin V binding GO:0031489
Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.
|
9 | P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) |
Myosin heavy chain binding GO:0032036
Interacting selectively and non-covalently with a heavy chain of a myosin complex.
|
9 | P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) |
Myosin II heavy chain binding GO:0032038
Interacting selectively and non-covalently with a heavy chain of a myosin II complex.
|
9 | P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
9 | P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | O14008 (/ISM) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Actin filament-based movement GO:0030048
Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
|
10 | O14008 (/IC) P54357 (/IC) P54357 (/IC) P54357 (/IC) P54357 (/IC) P54357 (/IC) P54357 (/IC) P54357 (/IC) P54357 (/IC) P54357 (/IC) |
Actomyosin contractile ring assembly GO:0000915
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
9 | P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) |
Actomyosin contractile ring assembly GO:0000915
The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
|
9 | P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) |
Vesicle targeting GO:0006903
The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.
|
9 | P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) |
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
|
9 | P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) P53141 (/IMP) |
Actin filament-based movement GO:0030048
Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
|
9 | P54357 (/IDA) P54357 (/IDA) P54357 (/IDA) P54357 (/IDA) P54357 (/IDA) P54357 (/IDA) P54357 (/IDA) P54357 (/IDA) P54357 (/IDA) |
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | Q9XVI9 (/IMP) |
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
|
1 | Q8VZ50 (/IEP) |
Ascospore formation GO:0030437
The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
|
1 | O14008 (/IMP) |
Ascospore-type prospore membrane assembly GO:0032120
The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
|
1 | O14008 (/IMP) |
Protein localization to medial cortex GO:0071574
A process in which a protein is transported to, or maintained in, the medial cortex.
|
1 | Q09196 (/IMP) |
Mitotic actomyosin contractile ring assembly GO:1903475
Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.
|
1 | Q09196 (/IMP) |
Mitotic actomyosin contractile ring assembly actin filament organization GO:1903479
Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly.
|
1 | Q09196 (/IMP) |
There are 33 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Myosin II complex GO:0016460
A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.
|
18 |
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P53141 (/IPI)
P54357 (/IPI)
(8 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
9 | P54357 (/TAS) P54357 (/TAS) P54357 (/TAS) P54357 (/TAS) P54357 (/TAS) P54357 (/TAS) P54357 (/TAS) P54357 (/TAS) P54357 (/TAS) |
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
|
9 | P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) |
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
|
9 | P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) |
Myosin V complex GO:0031475
A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.
|
9 | P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) |
Myosin VI complex GO:0031476
A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
|
9 | P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) |
Myosin VII complex GO:0031477
A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.
|
9 | P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) P54357 (/IPI) |
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
|
9 | P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) |
MIH complex GO:0120155
A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.
|
9 | P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) P53141 (/IDA) |
MIH complex GO:0120155
A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.
|
9 | P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) P53141 (/IPI) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | O14008 (/IDA) Q09196 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | Q8VZ50 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
5 | Q8VZ50 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) Q94AZ4 (/IDA) |
Cellular bud neck contractile ring GO:0000142
A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.
|
2 | A0A1D8PSE1 (/IDA) A0A1D8PSE1 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | O14008 (/HDA) Q09196 (/HDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O14008 (/HDA) Q09196 (/HDA) |
Spitzenkorper GO:0031521
Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.
|
2 | A0A1D8PSE1 (/IDA) A0A1D8PSE1 (/IDA) |
Cellular bud neck polarisome GO:0031560
Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.
|
2 | A0A1D8PSE1 (/IDA) A0A1D8PSE1 (/IDA) |
Cellular bud tip polarisome GO:0031561
Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.
|
2 | A0A1D8PSE1 (/IDA) A0A1D8PSE1 (/IDA) |
Prospore membrane GO:0005628
The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
|
1 | O14008 (/IDA) |
Actomyosin contractile ring GO:0005826
A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.
|
1 | Q09196 (/IDA) |
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
1 | O14008 (/IDA) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
1 | Q9XVI9 (/IDA) |
Myosin II complex GO:0016460
A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.
|
1 | Q09196 (/IDA) |
Medial cortex GO:0031097
A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
|
1 | O14008 (/IDA) |
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
|
1 | Q09196 (/HDA) |
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
|
1 | O14008 (/IDA) |
Myosin I complex GO:0045160
A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement.
|
1 | O14008 (/IDA) |
Cell tip GO:0051286
The region at the end of the longest axis of a cylindrical or elongated cell.
|
1 | O14008 (/IDA) |
Medial cortical node GO:0071341
A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.
|
1 | Q09196 (/IDA) |
Mitotic actomyosin contractile ring GO:0110085
A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.
|
1 | Q09196 (/IDA) |
Actin fusion focus GO:1990819
A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.
|
1 | O14008 (/IDA) |