The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 154: Reticulocalbin 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q8BH97 (/ISS) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q96D15 (/IDA) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q8BH97 (/ISO) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q96D15 (/IPI) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein secretion GO:0009306
The controlled release of proteins from a cell.
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q8BH97 (/ISS) |
Positive regulation of peptidase activity GO:0010952
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q8BH97 (/ISS) |
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q96D15 (/ISS) |
Collagen biosynthetic process GO:0032964
The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q8BH97 (/ISS) |
ERAD pathway GO:0036503
The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q96D15 (/ISS) |
Surfactant homeostasis GO:0043129
Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli.
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q96D15 (/ISS) |
Phospholipid homeostasis GO:0055091
Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q96D15 (/ISS) |
Lung epithelium development GO:0060428
The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
|
3 | I6L9G5 (/ISS) Q2KJ39 (/ISS) Q96D15 (/ISS) |
Protein secretion GO:0009306
The controlled release of proteins from a cell.
|
1 | Q96D15 (/IMP) |
Protein secretion GO:0009306
The controlled release of proteins from a cell.
|
1 | Q8BH97 (/ISO) |
Positive regulation of peptidase activity GO:0010952
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
|
1 | Q96D15 (/IMP) |
Positive regulation of peptidase activity GO:0010952
Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
|
1 | Q8BH97 (/ISO) |
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q8BH97 (/IMP) |
Collagen biosynthetic process GO:0032964
The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
1 | Q96D15 (/IMP) |
Collagen biosynthetic process GO:0032964
The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
|
1 | Q8BH97 (/ISO) |
ERAD pathway GO:0036503
The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
|
1 | Q8BH97 (/IMP) |
Surfactant homeostasis GO:0043129
Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli.
|
1 | Q8BH97 (/IMP) |
Regulation of protein kinase B signaling GO:0051896
Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | Q96D15 (/IMP) |
Regulation of protein kinase B signaling GO:0051896
Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | Q8BH97 (/ISO) |
Phospholipid homeostasis GO:0055091
Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.
|
1 | Q8BH97 (/IMP) |
Lung epithelium development GO:0060428
The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
|
1 | Q8BH97 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | Q8BH97 (/IDA) Q96D15 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | I6L9G5 (/ISS) Q2KJ39 (/ISS) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q8BH97 (/ISO) |