The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 112: EF-hand domain family, member D2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
7 | Q96C19 (/HDA) Q96C19 (/HDA) Q96C19 (/HDA) Q96C19 (/HDA) Q96C19 (/HDA) Q96C19 (/HDA) Q96C19 (/HDA) |
|
Calcium ion sensor activity GO:0061891
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).
|
2 | Q9BUP0 (/IMP) Q9BUP0 (/IMP) |
|
Calcium ion sensor activity GO:0061891
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).
|
2 | Q17QM6 (/ISS) Q9D4J1 (/ISS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9D8Y0 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9D8Y0 (/IPI) |
|
Calcium ion sensor activity GO:0061891
Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).
|
1 | Q9D4J1 (/ISO) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
5 | Q9VJ26 (/IEP) Q9VJ26 (/IEP) Q9VJ26 (/IEP) Q9VJ26 (/IEP) Q9VJ26 (/IEP) |
|
Regulation of cellular hyperosmotic salinity response GO:1900069
Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.
|
2 | Q9BUP0 (/IMP) Q9BUP0 (/IMP) |
|
Regulation of cellular hyperosmotic salinity response GO:1900069
Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.
|
2 | Q17QM6 (/ISS) Q9D4J1 (/ISS) |
|
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q9D4J1 (/IMP) |
|
Regulation of cellular hyperosmotic salinity response GO:1900069
Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.
|
1 | Q9D4J1 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | Q9VJ26 (/IDA) Q9VJ26 (/IDA) Q9VJ26 (/IDA) Q9VJ26 (/IDA) Q9VJ26 (/IDA) |
|
Muscle tendon junction GO:0005927
A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.
|
5 | Q9VJ26 (/IDA) Q9VJ26 (/IDA) Q9VJ26 (/IDA) Q9VJ26 (/IDA) Q9VJ26 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q9BUP0 (/TAS) Q9BUP0 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9D4J1 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q9D4J1 (/IDA) |
