The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Frizzled cysteine-rich domain
".
FunFam 24: Transmembrane receptor LIN-17
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
|
2 | G5EDV1 (/IPI) Q95Y45 (/IPI) |
There are 30 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Morphogenesis of an epithelium GO:0002009
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Regulation of asymmetric cell division GO:0009786
Any process that modulates the frequency, rate or extent of asymmetric cell division.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Regulation of asymmetric cell division GO:0009786
Any process that modulates the frequency, rate or extent of asymmetric cell division.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Polarity specification of anterior/posterior axis GO:0009949
Any process resulting in the establishment of polarity along the anterior/posterior axis.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Polarity specification of anterior/posterior axis GO:0009949
Any process resulting in the establishment of polarity along the anterior/posterior axis.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Polarity specification of proximal/distal axis GO:0010085
Any process resulting in the establishment of polarity along the proximal/distal axis.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Polarity specification of proximal/distal axis GO:0010085
Any process resulting in the establishment of polarity along the proximal/distal axis.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Anterior/posterior axon guidance GO:0033564
The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Anterior/posterior axon guidance GO:0033564
The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Regulation of vulval development GO:0040028
Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Regulation of vulval development GO:0040028
Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Hermaphrodite genitalia development GO:0040035
The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Hermaphrodite genitalia development GO:0040035
The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Regulation of cell fate specification GO:0042659
Any process that mediates the adoption of a specific fate by a cell.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Nematode male tail tip morphogenesis GO:0045138
The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Establishment of anatomical structure orientation GO:0048560
The process that determines the orientation of an anatomical structure with reference to an axis.
|
2 | G5EDV1 (/IGI) Q95Y45 (/IGI) |
Establishment of anatomical structure orientation GO:0048560
The process that determines the orientation of an anatomical structure with reference to an axis.
|
2 | G5EDV1 (/IMP) Q95Y45 (/IMP) |
Canonical Wnt signaling pathway GO:0060070
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
|
2 | G5EDV1 (/ISS) Q95Y45 (/ISS) |
Interneuron axon guidance GO:0097376
The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.
|
1 | G5EDV1 (/IGI) |
Interneuron axon guidance GO:0097376
The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.
|
1 | G5EDV1 (/IMP) |
Neuroblast migration GO:0097402
The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
|
1 | G5EDV1 (/IGI) |
Neuroblast migration GO:0097402
The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
|
1 | G5EDV1 (/IMP) |
Motor neuron migration GO:0097475
The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
|
1 | G5EDV1 (/IGI) |
Interneuron migration GO:1904936
The orderly movement of an interneuron from one site to another.
|
1 | G5EDV1 (/IGI) |
Positive regulation of motor neuron migration GO:1905485
Any process that activates or increases the frequency, rate or extent of motor neuron migration.
|
1 | G5EDV1 (/IGI) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | G5EDV1 (/IDA) Q95Y45 (/IDA) |
Neuron projection membrane GO:0032589
The portion of the plasma membrane surrounding a neuron projection.
|
2 | G5EDV1 (/IDA) Q95Y45 (/IDA) |