The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"c-terminal domain of poly(a) binding protein
".
FunFam 6: Polyadenylate-binding protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
14 |
E9AFP0 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
(4 more) |
|
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
|
14 |
E9AFP0 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
(4 more) |
|
Telomeric DNA binding GO:0042162
Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
|
10 | O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) |
|
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
|
3 | E9AFP0 (/IDA) E9AFX7 (/IDA) Q4QA88 (/IDA) |
|
Eukaryotic initiation factor 4G binding GO:0031370
Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.
|
3 | E9AFP0 (/IDA) E9AFX7 (/IDA) Q4QA88 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | E9AFP0 (/IPI) Q4QA88 (/IPI) |
|
Poly(A) binding GO:0008143
Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
|
1 | Q54BM2 (/ISS) |
|
Eukaryotic initiation factor 4E binding GO:0008190
Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.
|
1 | E9AFX7 (/IPI) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
|
14 |
E9AFP0 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
O96971 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
Q38DU2 (/ISA)
(4 more) |
|
Posttranscriptional regulation of gene expression GO:0010608
Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
|
13 |
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
(3 more) |
|
Regulation of translational initiation GO:0006446
Any process that modulates the frequency, rate or extent of translational initiation.
|
3 | Q38E63 (/ISA) Q38E63 (/ISA) Q38E63 (/ISA) |
|
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
|
1 | E9AFX7 (/IDA) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
16 |
E9AFP0 (/IDA)
E9AFX7 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
(6 more) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
13 |
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
O96971 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
Q38DU2 (/IDA)
(3 more) |
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
10 | O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) |
|
Nuclear stress granule GO:0097165
A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
|
10 | O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) O96971 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) Q38DU2 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | E9AFP0 (/ISO) E9AFX7 (/ISO) Q38E63 (/ISO) Q38E63 (/ISO) Q38E63 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | E9AFP0 (/IDA) E9AFX7 (/IDA) Q4QA88 (/IDA) |
|
Cytoplasmic stress granule GO:0010494
A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
|
2 | E9AFP0 (/ISO) E9AFX7 (/ISO) |
|
P-body GO:0000932
A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
|
1 | E9AFP0 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q54BM2 (/ISS) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | Q54BM2 (/HDA) |
|
Nuclear stress granule GO:0097165
A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
|
1 | E9AFP0 (/ISO) |
